Stefania Benonisdottir, lead author of the study and a Doctoral candidate from the Big Data Institute, explains, ‘Currently, most genetic studies are based on genetic databases which contain large numbers of participants and a wealth of information. However, such studies can be affected by biases, which arise when genetic databases are not representative of the intended study population. Now, the identified genetic inclination to participate can help scientists assess the representativeness of their study sample. The study also found the genetic component of participation can be passed down through families and may affect people's participation in many different studies over their lifetimes. This highlights the potential for bias in genetic research and underscores the importance of accounting for such biases in study design and analysis.