This initiative builds on the work of a Wellcome Trust-funded consortium including Public Health Wales, the University of Cardiff, and Public Health England. This adds a new dimension in our ability to process pathogen data. The SP3 system will now deliver comprehensive and standardised results of COVID-19 analyses within minutes of submission on an international scale. 'The opportunity of applying systematic examination for genetic variants in a range of pathogens will have major benefits for global public health. This could potentially have a far-reaching positive impact on international public health and global health security.