More than 1 million patients in the analysis had immune mediated inflammatory diseases (IMIDs). These included inflammatory bowel disease such as Crohn’s disease and ulcerative colitis, conditions affecting the joints such as rheumatoid arthritis, and skin conditions including psoriasis. People with inflammatory joint disease appeared to be at greatest risk compared to those with gut or skin disease. 'Our study provides the most accurate assessment of risk of severe COVID-19 before vaccination in people with IMIDs and with the drugs used for their treatment. The team also investigated the impact of certain medication, identifying around 200,000 people who were on immune modifying drugs.
