Research Technician

University of York
April 10, 2024
Offerd Salary:£30,487
Working address:N/A
Contract Type:Other
Working Time:Full time
Working type:N/A
Ref info:N/A
Research Technician




£30,487 per year


Grade 5

Contract status

Fixed term

Hours of work


Based at

University of York campus

Interview date

To be confirmed

Posted Date


Apply by


Job Reference



  • Job description 13271.pdf (PDF, 284.02kb)
  • Role Description Department

    Applications are invited for a technician for up to 12 months to support the group's efforts in understanding the molecular mechanism of dsDNA virus assembly using bacteriophage HK97 as a model system. You will work in the York Structural Biology Laboratory within the Department of Chemistry, providing technical and scientific support to the research project.

    The Department of Chemistry is one of the largest and most successful departments at York and we are renowned internationally for our research. As a department, we strive to provide a working environment that allows all staff and students to contribute fully, to flourish, and to excel. We are proud of our Athena SWAN Gold Award.


    You will: (i) produce and purify bacteriophage HK97 capsids as well as DNA motor proteins and their mutant variants; (ii) assemble stable DNA-packaging assemblies, (iii) determine 3D structure using cryo-EM and (iv) analyse structural data to understand the molecular mechanism of DNA packaging.

    Key responsibilities will include: -

  • Work effectively on own initiative and also with other staff and students to help solve problems
  • Plan and perform experiments using a range of scientific techniques
  • Be responsible for the maintenance, modification, repair and operation of technical equipment, liaise with appropriate staff and external service providers as required
  • Pro-actively update and improve processes, maintain accurate records, contribute to the development of protocols, standard operating procedures and maintenance schedules
  • Understand, promote and apply COSHH/Risk Assessment and departmental health and safety protocols ensuring procedures are followed at all times
  • Manage a small budget, monitor resource usage, assist with purchasing including ordering and distributing goods
  • Provide inductions, training and demonstrations of specialist techniques ensuring compliance with safety and regulatory guidelines
  • Skills, Experience & Qualification needed
  • HNC, HND, Degree or equivalent in appropriate science discipline or experience
  • RSciTech / EngTech or willingness to work towards these or equivalent professional qualifications
  • In depth knowledge of relevant safety regulations and procedures for example, COSHH and risk assessment
  • Familiarity with structure determination by EM using single-particle 3D reconstruction with RELION
  • Experience in virology and molecular biology, in particular purification of virus particles and production and purification of individual proteins
  • Competent in the use of advanced technical equipment and techniques using a variety of specialist technical skills
  • Ability to analyse and interpret data and explain complex information to others
  • Experienced in producing procapsids of viruses, assessing and modifying the nuclease activity of DNA packaging terminase
  • Good interpersonal skills with the ability to communicate effectively and maintain a positive, open attitude towards others
  • Actively demonstrates a commitment to professional development
  • Dependable, reliable and self-motivated
  • Commitment to and understanding of equality, diversity and inclusion issues
  • Interview date: To be confirmed

    For informal enquiries: please contact Prof Fred Antson on [email protected]

    The University strives to be diverse and inclusive – a place where we can ALL be ourselves.

    We particularly encourage applications from people who identify as Black, Asian or from a Minority Ethnic background, who are underrepresented at the University.

    We offer family friendly, flexible working arrangements, with forums and inclusive facilities to support our staff. #EqualityatYork

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