Research Technician

University of York
March 07, 2024
Offerd Salary:£30,487 - £34,980
Working address:N/A
Contract Type:Other
Working Time:Part time
Working type:N/A
Ref info:N/A
Research Technician




£30,487 - £34,980 a year, reduced pro-rata for part time working


Grade 5

Contract status

Fixed term

Hours of work


Based at

University of York campus

Interview date

14th March 2024

Posted Date


Job Reference



  • Job Description 13100.pdf (PDF, 298.63kb)
  • Role Description Department

    You will be a member of the Department of Biology, which is one of the UK's leading Biology departments, and renowned internationally for our research. This is combined with a commitment to teaching and outstanding student satisfaction, and we have been recognised consistently for our family-friendly policies and are proud of our Athena SWAN Gold Award. We aim to ensure that there is a supportive culture across all staff groups and levels. We promote good practice and a strong culture of equality in higher education. Further information can be found on our website (https:// www. We want to recruit the best people for our roles, and there is flexibility on how the 0.5FTE of this role is split across the days of the week.


    We are looking for a Research Technician to join a new project engineering gene regulatory networks to design disease resistant crops. The project is a collaboration between Katherine Denby's group at the University of York, Nicola Patron at the University of Cambridge and Richard Morris at the John Innes Centre. We have modelled and validated a gene regulatory network underlying the lettuce transcriptional defence response to fungal pathogens, which has identified several regulators of the defence response (both positive and negative) and their downstream target genes. In this collaborative project we will further validate and refine the gene regulatory network, use computational modelling to predict network re-wiring to maximise plant resistance to infection, implement the re-wiring using gene editing and synthetic genetic controllers, and test in protoplasts and transgenic lettuce. This research technician post will work alongside a PDRA at York providing plant and molecular biology expertise.

    The main duties and responsibilities of this role will be:

  • To provide technical and scientific support to this project, involving in vitro and protoplast-based techniques for network validation, build network re-wiring constructs and test them in lettuce protoplasts and gene-edited lettuce lines. You will work under your own initiative as well as part of a wider team.
  • To maintain accurate records of work undertaken and communicate results via reports or presentations.
  • To understand, promote and apply COSHH/Risk Assessment, departmental health and safety protocols.
  • Skills, Experience & Qualification needed

    Degree or equivalent in biological sciences or appropriate experience

  • Knowledge of plant molecular biology and ability to implement a range of practical techniques used in plant science
  • Ability to perform complex technical tasks to a consistently high standard with attention to detail, and to keep detailed records of activities and use these to improve procedures
  • In depth knowledge of relevant safety regulations and procedures for example, COSHH and risk assessment, and good microbiological practice
  • Good interpersonal skills and ability to maintain a positive, open attitude toward others, to value and support colleagues
  • Interview date: 14th March 2024

    For informal enquiries: please contact Katherine Denby on [email protected]

    The University strives to be diverse and inclusive – a place where we can ALL be ourselves.

    We particularly encourage applications from people who identify as Black, Asian or from a Minority Ethnic background, who are underrepresented at the University.

    We offer family friendly, flexible working arrangements, with forums and inclusive facilities to support our staff. #EqualityatYork

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