Research Associate in flow cytometric preparation and analysis of mitotic chromosomes

University of Oxford
April 30, 2024
Offerd Salary:£36,024 - £44,263
Working address:N/A
Contract Type:Fixed Term Contract
Working Time:Full time
Working type:N/A
Ref info:N/A

Research Associate in flow cytometric preparation and analysis of mitotic chromosomes

Department of Biochemistry, South Parks Road, Oxford


Salary (£) : £36,024 - £44,263 per annum

Location: Department of Biochemistry, South Parks Road, Oxford

Contract type: Fixed Term Contract for up to 2 years in the first instance

Hours: Full Time (37.5 hours per week)

About the role

We are seeking to appoint a Research Associate to join the research group of Prof Amanda Fisher to support an interdisciplinary team working at the intersection between chromosome biology, flow cytometry, microfluidics and molecular/epigenetic analysis. The group's current work focuses on determining the repertoire and role of proteins that remain bound to mitotic chromosomes through cell division. This uses molecular, genetic and biochemical approaches to disrupt and/or degrade mitotic proteins and evaluate the relevance of such factors in determining chromosome structure and the transmission of cellular identity. To do this we develop new ways of isolating and manipulating native mitotic chromosomes from different organisms using flow cytometry and microfluidic approaches, and then interrogate the function of proteins postulated to ‘bookmark' the genome through mitosis. We are looking for a dedicated individual to lead the development of technology in this area, supported by existing close collaborations with staff at the MRC LMS.

This full-time fixed-term post is funded by the Medical Research Council for up to 2 years in the first instance.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

What We Offer

Your happiness and wellbeing at work matters to us, so we offer a range of family friendly and financial benefits including:

• An excellent contributory pension scheme

• 38 days annual leave

• A comprehensive range of childcare services

• Family leave schemes

• Cycle loan scheme

• Membership to a variety of social and sports clubs

• Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.

About you

Applicants should hold a BSc or MSc degree in a relevant subject area related to Biology, biotechnology, photonics or biophysics and possess sufficient specialist knowledge to work within the established research programme. You will have knowledge and experience in molecular, cellular or chromosome biology and have the capacity to learn and develop skills in cytometry and have a rigorous approach to data collection and reproducibility. Experimental and analysis skills are essential as is having the capacity to communicate with others and conveying information in a clear and concise manner. You will have excellent verbal and written communication skills and have the ability to work as part of a team and individually.

Application Process

You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of three referees as part of your online

Only applications received before 12 noon on Tuesday 30th April 2024 can be considered with interviews for shortlisted candidates to be held as soon as possible thereafter.

Committed to equality and valuing diversity

Contact Person : HR Officer Vacancy ID : 172127 Contact Phone : Closing Date & Time : 30-Apr-2024 12:00 Pay Scale : STANDARD GRADE 7 Contact Email : [email protected] Salary (£) : 36024 - 44263

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