The Ahringer lab in the Gurdon Institute is looking for an experienced laboratory research scientist with expertise in molecular biology and genomics to support its research programmes. We decipher how chromatin and gene expression are regulated to direct the step-by-step development of the single- celled totipotent zygote to the differentiated state. We use the C. elegans model, where the invariant lineage makes it the only organism where it is feasible to determine cell-to-cell genomic regulatory transitions across development. We apply single cell profiling, bulk genomic assays, microscopy, and mutant analyses to determine how the genome is regulated to drive developmental decisions and their expression.
This is a key role that will offer collaborative support and technical expertise across the scientific programmes in the laboratory. The role covers a wide range of activities, allowing for continuity of lab operations. Activities include:
This is a highly collaborative position, so excellent communication and interpersonal skills are essential. You should be a motivated and organised individual with expertise in a broad range of molecular biology techniques and have the ability to work both independently and as part of a team. Experience in genomic profiling techniques (e.g. ChIP-seq, ATAC-seq, RNA-seq, single cell analyses) is highly desirable. Candidates should have a PhD in a relevant discipline and have a capacity to apply initiative and creativity to solve technical and biological problems.
The Gurdon Institute is a world-renowned centre of Developmental biology and Cancer research embedded in the University of Cambridge. It provides an exceptional and stimulating environment that promotes collaborative and interdisciplinary research in a supportive and modern setting, with access to state-of-the-art technologies such as super-resolution imaging, single-cell analyses, genome engineering, and genomics and computer modelling.
Informal enquiries can be made to Julie Ahringer via [email protected]
If you have any questions about this vacancy or the application process, please contact [email protected].
Fixed-term: The funds for this post are available until 31 December 2025 in the first instance.
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Please quote reference PR41123 on your application and in any correspondence about this vacancy.
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Further informationWellcome Trust/Cancer Research UK Gurdon Institute
Salary£36,024-£44,263
ReferencePR41123
CategoryResearch
Published28 March 2024
Closing date28 April 2024