The Medical Research Council Mitochondrial Biology Unit (MRC MBU), University of Cambridge wishes to appoint a post-doctoral Research Associate to join Dr Alex Whitworth and the Mitochondrial Neurodegeneration group.
A world-renowned centre for research, the MRC MBU is a vibrant community focused on the involvement of mitochondria and their dysfunction in an ever- increasing range of human diseases. Additional information can be found at www. mrc-mbu.cam.ac.uk.
The Mitochondrial Neurodegeneration group pursues an integrated, multi- disciplinary programme of investigations to understand the homeostatic mechanisms that regulate the integrity of mitochondria and maintain normal neuronal function and survival. The group uses Drosophila and cellular models to elucidate the molecular mechanisms of pathogenesis of various neurodegenerative diseases such as Parkinson's Disease, Huntington's Disease and Motor Neuron Disease. We are now expanding our model repertoire to include mouse and human iNeuron models.
The post-holder will lead one or more projects analysing the role of mitochondrial ion handling (mainly, calcium and iron via MCU and CISD1 proteins) in normal physiology and the contribution to neurodegenerative diseases. The projects will focus on the use of mouse models and human iNeurons. The post-holder will be expected to play a major role in the work of the research group, through the conduct of research, introduction of new ideas, dissemination of research results, support and training of others. Candidates will have (or be about to be awarded) a PhD in molecular or cellular biology or similar discipline, and a track record of related research achievements.
Informal enquires about this position should be directed to Dr Alex Whitworth ([email protected]).
This is a fixed term post until 31 March 2027.
Applicants should include a CV and cover letter detailing why they are suitable for the position and their experience, along with contact information for three professional referees who can be contacted prior to interview.
The University of Cambridge is committed, in its pursuit of academic and research excellence, to a pro-active and inclusive approach to equality, which supports and encourages all under-represented groups, promotes an inclusive culture, and values diversity. The MBU is part of the School of Clinical Medicine, which holds an Athena Swan Silver Award and supports an Academic Women's Forum. The University particularly encourages women and candidates from Black, Asian and Minority Ethnic backgrounds to apply.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Applicants must have (or be close to obtaining) a PhD.
Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will initially be appointed as a Research Assistant (Grade 5, Point 38 £31,411) moving to Research Associate (Grade 7) upon confirmation of your PhD award.
Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
Please quote reference SM42000 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Further informationMRC Mitochondrial Biology Unit
Salary£36,024-£44,263
ReferenceSM42000
CategoryResearch
Published9 June 2024
Closing date9 July 2024