Exciting opportunity for an enthusiastic Research Assistant with an interest in Neuroscience to work on a project focusing on the development of novel gene therapies for the treatment of epilepsy
Salary Package: From $80,753 - $91,815 (HEW 5) plus 17% superannuation and annual leave loading
Appointment Type: Fixed Term Contract (12m with potential extension)
Location: Macquarie University (Wallumattagal Campus, North Ryde)
We are seeking an enthusiastic Research Assistant with an interest in neuroscience and neurological disorders to contribute to a NHMRC-funded project aiming to develop novel gene therapies for the treatment of epilepsy. The researcher will also assist with ongoing projects investigating the mechanisms underlying neurological disorders, such as dementia. The successful applicant will provide experimental and resource support on a wide range of research activities, including behavioural and biochemical analysis of mice, cell culture and analysis, molecular biology and cloning, testing and analysis of AAV gene therapies. The Research Assistant will work directly with Senior Academics at the Dementia Research Centre and will liaise with a range of research and administrative staff. This should appeal to a highly motivated individual who is keen to contribute exceptional efforts to a research team in neuroscience and treatment development.
Specific role requirements:
Carry out, and assist with, biochemical analysis of biological resources (including cell culture and animal tissue) using a variety of research techniques such as Western blotting, immunohistochemistry, PCR, protein extraction etc.
Undertake molecular biology experiments such as: RT-PCR, DNA/RNA extractions, molecular cloning and modification of DNA plasmids.
Culturing, treating and analysis of cultured cells, both immortalized cell lines and primary cells, with techniques including immunocytochemical staining, western blot etc.
Assist with the maintenance and monitoring of a large mouse colony to a high standard. This includes assisting with setting up of breedings, monitoring pregnancies, weaning offspring, tissue harvesting, record keeping and genotyping of mice.
Assist with, and carry out, behavioural testing of mice including adequate monitoring of mice throughout the testing period and analysis of behavioural data.
Work efficiently and effectively as part of a team to help support senior researchers, as well as working independently, to complete research projects to a high scientific standard.
Maintain appropriately detailed and accurate records of experiments and proficient management of data.
Comply with relevant EEO and WHS regulations.
The successful applicant will have a proven record of excellent standard of laboratory research, data analysis, record keeping and communication skills. You can work with minimum supervision, show initiative, and anticipate requirements, ensuring deadlines and objectives are met. Previous experience in the behavioural and biochemical analysis of mice, including immunocytochemistry and animal handling, is highly desirable. You will bring to the role knowledge of various laboratory techniques, including protein biochemistry, molecular biology, histology, cell culture and/or microscopy. You can use strong written and verbal communication and organisational skills to liaise with various stakeholders and assist in the preparation of research data for presentation and publication.
Macquarie University's Faculty of Medicine, Health and Human Sciences builds on the aspiration to have the nation's first fully integrated Academic Health Sciences Centre under a university's leadership. It brings together the excellent work of medical and allied-health clinicians and researchers across the University and around the country, with unparalleled access to world- leading clinical resources and research facilities found only on our campus.
Within the Faculty, the Dementia Research Centre provides an environment for innovative, interdisciplinary research for dementia and other neurological conditions, using and developing state-of-the-art technologies to advance basic discoveries towards translation into clinical treatments. The Dementia Research Centre is committed to providing a unique and supportive mentoring program to allow the growth of future leaders for dementia research.
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To be considered for this position, please apply online by submitting your cv and a separate (2-page maximum) cover letter that demonstrates how you meet the following selection criteria:
Bachelor's degree or higher in medical science, neuroscience, biochemistry or related discipline.
Experience in the handling and analysis of research animals for scientific purposes, including behavioural and biochemical analysis, highly desireable.
Experience with techniques such as PCR, DNA and protein extraction, Western blotting, immunohistochemistry, molecular biology and similar methods highly desireable.
Experience in microscopy techniques, such as confocal and fluorescence microscopy desirable.
Highly motivated and driven individual who can work well independently, as well as part of a team.
Experience with working in a research laboratory, experimental planning and a thorough understanding of laboratory health and safety practices and principles.
Excellent organisational skills with a demonstrated capacity to meet tight deadlines and manage time effectively.
Strong written and verbal communication and organisational skills to assist in the preparation of research data.
This position requires you to comply with occupational screening, assessment and vaccinations in line with Macquarie University health requirements.
Please note this position is only open to Australian citizens, permanent residents and those currently residing in Australia with full working rights.
Specific Role Enquiries: Janet van Eersel, Group Leader in Drug Discovery on [email protected]
General Enquiries: Amie Law, Centre Manager in the Dementia Research Centre on [email protected]
Applications Close : Sunday 18 February 2024 at 11:59 PM AEDT
If you're already part of the Macquarie Group (MQ University, U@MQ, MQ Health, MGSM), you'll need to apply through your employee Workday account. To apply for this job: Login to Workday and go to the Careers App > Find Jobs.
18/02/2024 11:59 PM
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