COLLEGE OF MVLS
SCHOOL of Cancer Sciences
Research Assistant (Grade 6) or Postdoctoral Research Associate (Grade 7)
To make a leading contribution to the CRUK-funded programme “Reconstructing the Evolution of Mesothelioma for Improved Treatment”, working under the mentorship of Professor Daniel J. Murphy within the REMIT and PREDICT-Meso research consortium. Mesothelioma is a devastating cancer of the chest cavity that arises decades after occupational exposures to asbestos. The Murphy lab excels is using GM mouse models for mechanistic investigation of tumour biology and cancer development. This project will apply a range of state-of- the-art methodologies to a temporal dissection of in vivo cancer evolution, from incipient pre-cancerous lesions through to development of malignancy, to identify tumour cell dependencies that can be exploited for clinical translation and improved treatment of Mesothelioma patients. The successful candidate will work as part of an international team and will be expected to contribute to the formulation and submission of research publications and research proposals as well as to help manage and direct this complex and challenging project as opportunities allow. Pls visit https: // www. predictmeso.com/ for more information on the Mesothelioma research consortium.
Main Duties and Responsibilities
1. Plan and conduct assigned research individually or jointly in accordance with REMIT project deliverables and Murphy lab/School of Cancer Sciences/MVLS research strategy.
2. To maintain healthy colonies of complex multi-allelic GM mice, including strict adherence to HO licenced protocols, AWERB guidelines, and Murphy lab/CRUK Beatson Institute SOPs
3. Document research output including analysis and interpretation of all data, maintaining records and databases, drafting technical/progress reports and papers as appropriate.
4. Develop and enhance your research profile and reputation and that of The University of Glasgow/School of Cancer Sciences/Murphy Lab, including contributing to publications of international quality in high profile/quality refereed journals, enhancing the research impact in terms of economic/societal benefit, and gathering indicators of esteem.
5. Contribute to the presentation of work at international and national conferences, at internal and external seminars, colloquia and workshops to develop and enhance our research profile. 6. Contribute to the identification of potential funding sources and to assist in the development of proposals to secure funding from internal and external bodies to support future research.
7. Collaborate with colleagues and participate in Murphy lab, REMIT team & PREDICT-Meso group meetings/seminars/workshops across the Mesothelioma research community/School of Cancer Sciences/College of MVLS/University and wider community.
8. Contribute to the organisation, supervision, mentoring and training of undergraduate and/or postgraduate students and less experienced members of the project team to ensure their effective development.
9. Perform administrative tasks related to the activities of the research group and School, including Budgets/Expenditure. 10. Carry out modest Teaching activities (e.g. practical demonstration) and associated admin as assigned by the Head of School and in consultation with Principal Investigator.
11. Keep up to date with current knowledge and recent advances in Cancer Research, in particular Mesothelioma & Cancer Inflammation/Immunology.
12. Engage in continuing professional development activities as appropriate.
13. Undertake any other duties of equivalent standing as assigned by the Head of School/Director of Research Institute.
14. Contribute to the enhancement of the University's international profile in line with the University's Strategic Plan, Inspiring People Changing the World.
For appointment at grade 7 :
15. Perform the above duties with a higher degree of independence, leadership and responsibility, particularly in relation to planning, funding, collaborating and publishing research, and mentoring colleagues.
16. Establish and sustain a track record of independent and joint published research to establish and maintain your expert reputation in the subject area.
17. Survey the research literature and environment, understand the research challenges associated with the project & subject area, & develop/implement a suitable research strategy.
A1 SCQF Level 10 (Honours degree) in a relevant subject or a cognate discipline, or equivalent.
A2 Specialist theoretical and practical knowledge of Cancer Research Methodologies
A3 A comprehensive and up-to-date knowledge of Cancer Biology
Desirable: B1 A recently submitted (or near completion) Ph.D. thesis in Cancer Biology/Cancer Immunology/Inflammation in Cancer
For appointment at grade 7: Essential: A4 Normally Scottish Credit and Qualification Framework level 12 (i.e. Ph.D.) or alternatively possess the equivalent in professional qualifications and experience, with experience of personal development in a relevant similar or related role(s).
Knowledge, Skills and Experience
C1 A strong background in Cancer Biology/Cancer Immunology
C2 Research creativity and cross-discipline collaborative ability as appropriate.
C3 Excellent communication skills (oral and written), including public presentations and ability to communicate complex data/concepts clearly and concisely
C4 Excellent interpersonal skills including team working and a collegiate approach
C5 Appropriate workload/time/project/budget/people management skills
C6 Extensive IT and data analysis/interpretation skills as appropriate. C7 Self-motivation, initiative and independent thought/working
C8 Problem solving skills including a flexible and pragmatic approach
For appointment at Grade 7
C9 A comprehensive and up-to-date knowledge of current issues and future directions within Cancer Biology and/or Cancer Immunology research.
C10 Knowledge of genetically engineered mouse models and downstream analytical pipelines, including but not limited to, Quantitative Histology/IHC/Transcriptomic methodologies and analysis.
C11 Sufficient depth of relevant research experience, normally including sufficient postdoctoral experience in a related field, appropriate to an early career researcher.
D2 Knowledge of Inflammation-related biology, esp. as pertains to Cancer predisposition.
D3 Knowledge of HO animal research reporting requirements and an active HO Personal Licence (PIL).
E1 A minimum of 3 years practical experience in a relevant research laboratory setting.
E2 Project or subject specific experience
E3 Evidence of experience of scientific writing
E4 Proven ability to deliver quality outputs in a timely and efficient manner
E5 Evidence of an emerging track record of publications in a relevant field
For appointment at grade 7:
E6 An established track record of presentation and publication of research results in quality journals and/or conferences, appropriate for career stage.
E7 Experience of making a leading contribution in academic activities.
E8 Ability to demonstrate a degree of independence as illustrated by identification of project objectives from assessment of the literature, design & analysis of experiments & drafting of papers.
E9 Experience in undertaking independent research.
E10 Commitment to open research, as appropriate to the discipline, through open data, open code, open educational resources and practices that support replication.
E11 Demonstrable commitment to supporting the career development of colleagues and to other forms of collegiality appropriate to the career stage.
F1 Experience in maintaining and documenting complex GM mouse colonies.
F2 Experience in “Omic” data generation and interpretation, esp. Transcriptomic and proteomic.
F3 Experience in complex multi-channel FACS analysis.
Terms and Conditions
Salary will be Grade 6/7, £32,332 - £36,024/£39,347 - £44,263 per annum
This post is full time, and is funded for up to 46 months.
As part of Team UofG you will be a member of a world changing, inclusive community, which values ambition, excellence, integrity and curiosity.
As a valued member of our team, you can expect:
1 A warm welcoming and engaging organisational culture, where your talents are developed and nurtured, and success is celebrated and shared.
2 An excellent employment package with generous terms and conditions including 41 days of leave for full time staff, pension - pensions handbook https: // www. gla.ac.uk/myglasgow/payandpensions/pensions/, benefits and discount packages.
3 A flexible approach to working.
4 A commitment to support your health and wellbeing, including a free 6-month UofG Sport membership for all new staff joining the University https: // www. gla.ac.uk/myglasgow/staff/healthwellbeing/.
We believe that we can only reach our full potential through the talents of all. Equality, diversity and inclusion are at the heart of our values. Applications are particularly welcome from across our communities and in particular people from the Black, Asian and Minority Ethnic (BAME) community, and other protected characteristics who are under-represented within the University. Read more on how the University promotes and embeds all aspects of equality and diversity within our community https: // www. gla.ac.uk/myglasgow/humanresources/equalitydiversity/.
We endorse the principles of Athena Swan https: // www. gla.ac.uk/myglasgow/humanresources/equalitydiversity/athenaswan/ and hold bronze, silver and gold awards across the University.
We are investing in our organisation, and we will invest in you too. Please visit our website https: // www. gla.ac.uk/explore/jobs/ for more information.
Vacancy Ref : 137971 Close Date : 20-Feb-2024 23:45