postdoctoral appointment in chemistry interfacing bioengineering, biomedical, and life sciences
Location: Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA and Rodney Porter Building, Sibthorp Rd, off South Parks Road, Oxford, OX1 3QU
Salary: Grade 7, £ £37,524 - £45763 per annum
The Aye laboratory based at Oxford Department of Chemistry is a multidisciplinary laboratory focusing on reactive small-molecule metabolite signaling as it pertains to intra- and intercellular communication and drug discovery. We have pioneered numerous novel and multi-award-winning chemical biology concepts and techniques that have been applied to important biological questions.
The available projects for several postdoctoral appointments will build on previously-published foundational studies, and encompass wide-ranging areas in the broader context of organic chemistry and chemical biology including small- molecule probe engineering: including, (1) projects aimed at understanding and reprogramming subcellular metabolite trafficking and signaling mechanisms through the design and application of novel small- molecule probes; (2) projects targeting chemistry-driven innovations of advanced spatial & functional omics methods in multiple living models for fundamental and disease-specific investigations; (3) development of selective small-molecule inhibitors targeting proteins/pathways essential in anticancer and immunotherapeutic development. There is possibility to learn cell-based assays and cutting-edge biochemical assays, in line with candidates' interest to diversify and successful and timely production of desired molecules (and subsequent SAR)
Your profile: prospective candidates should have, by the time they begin work, a Ph.D. in chemistry or biological or medicinal chemistry, or broader life sciences. We welcome all interested aspiring interdisciplinary researchers with diverse backgrounds. Experience in organic chemistry, bioengineering, or biotechnology is a plus, but not strictly required.
We offer: a laboratory that has won numerous awards lying at a nexus between numerous fields interfacing with chemistry. The successful candidate will enjoy unique state-of-the-art instrumentation, a team-playing environment where they can learn and develop, and projects that are aiming to make real- world impact. The facilities and infrastructure at Oxford are also fantastic. More information about our research group, including other active research themes, can be found at https: // www. chem.ox.ac.uk/people/yimon-aye
Start date: For all positions, they are available immediately, funding is available, and the start date is flexible. All applications should include in PDF format: (i) Cover letter, (ii) CV, (iii) the contact information of three references.
Term of employment: full time initial one-year
Contact: For questions or additional information, please contact [email protected]
Contact Person : Anna Giorgi Vacancy ID : 175967 Contact Phone : Closing Date & Time : 29-Oct-2024 12:00 Pay Scale : RESEARCH GRADE 7 Contact Email : [email protected]