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MU
Postdoc Position

Postdoctoral Fellow

Marshall University · United States
Deadline
Mar 22, 2027
Closing in 154 days
Location
N/A
United States
Employment
None
Reference
N/A
Posted Sep 23, 2026

About the role

Postdoctoral Fellow

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Please see Special Instructions for more details.

Please include the following with your application:
  • A cover letter detailing research experience and interest in the position.
  • Curriculum Vitae (CV) with a publication list.

Position Details

Position Information
Banner Position Number R10910
Position Title Postdoctoral Fellow
Classification Title MURC-Biological Scientists
Department SOM-BioMedical Science - RC5130
Job Description Job Summary:
The Xu Lab in the Department of Biomedical Sciences is seeking a motivated and skilled Postdoctoral Fellow to join our team. The candidate will lead a research project focusing on molecular microbiology of infectious diseases. One focus of this role involves inhibitor design and validating these targets. The ideal candidate will possess extensive hands-on experience in microbial construct design, genetic transformation, recombinant protein expression, and targeting those proteins with biochemical inhibitors.

Key Responsibilities:
Inhibitor Design: Apply computational tools (docking, molecular dynamics) or experimental methods to design and screen small-molecule, peptide, or fragment-based inhibitors against target proteins.
  • Assay Development: Establish biochemical, biophysical, and cellular assays to measure inhibitor binding affinity and functional enzyme inhibition.
  • Construct Cloning: Design and construct expression plasmids, genetic vectors, and CRISPR-based tools for bacterial/host systems.
  • Strain Engineering: Engineer microbial strains and mammalian cells.
  • Protein Expression: Purify target proteins using chromatographic methods.
  • Characterization: Perform biochemical characterization, Western blotting, ELISA, and functional assays to validate protein activity.
Location MUSOM - Marshall University School of Medicine
Salary Range Salary is commensurate with experience and internal equity
Required Qualifications
Education
  • Ph.D. in Microbiology, Molecular Biology, Biochemistry, Medicinal Chemistry, or a closely related field.
Experience
  • Demonstrated experience in inhibitor design, structural biology, or biochemical assay development for target evaluation.
  • Proven expertise in molecular cloning techniques (Gibson assembly, restriction-based, PCR).
  • Hands-on experience with bacterial transformation and genetic manipulation.
  • Strong background in recombinant protein expression and purification.
  • Evidence of productivity: At least one first-author publication in a peer-reviewed journal.
  • Experience using structural biology or computational chemistry software (e.g., PyMOL, Schrödinger, AutoDock, Rosetta).
  • Experience with biophysical characterization techniques (e.g., SPR, ITC, MST).
  • Knowledge of bioinformatics tools for gene/protein analysis.
Preferred Qualifications
Education
Experience
Posting Detail Information
Posting Number MR0884
Open Date 07/23/2026
Close Date
Open Until Filled Yes
Special Instructions Summary Please include the following with your application:
  • A cover letter detailing research experience and interest in the position.
  • Curriculum Vitae (CV) with a publication list.

Supplemental Questions

Required fields are indicated with an asterisk (*).

  1. * Do you have a Ph.D. in Microbiology, Molecular Biology, Biochemistry, Medicinal Chemistry, or a closely related field?
    • Yes
    • No

Applicant Documents

Required Documents
  1. CV or Resume
Optional Documents
  1. Cover Letter

How to apply

Read the full posting, then apply through the employer's own site. Applications are handled by the institution, not by AcademicGates.

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