Do you want to contribute to top quality medical research?
Chemical Biology Consortium Sweden, CBCS, will from 2022 be a Swedish
Research Council funded infrastructure of national interest. This means that
the existing capabilities will be strengthened and new capabilities and four
new nodes - at Lund, Uppsala, Linköping and Gothenburg Universities,
respectively, will be established. CBCS (www. CBCS.se) has been in operation
since 2010 with two nodes at KI and at Umeå University, respectively, and is
an infrastructure for chemical biology at Science for Life Laboratory
(www. scilifelab.se) in the Chemical Biology and Genome Engineering platform.
CBCS offers services for the identification of chemical tools (bioactive
small-molecules) for all fields of life sciences. The infrastructure offers
collaborative service and guidance within assay development, small-molecule
screening and hit to chemical probe optimization. Additional service offerings
in small-molecule profiling, including Cell Painting, and screening in primary
and complex disease models are currently being established.
The KI node is currently seeking a versatile biologist skilled in assay
development and small molecule screening who will help CBCS in its mission
of identifying, developing and optimizing high-quality small molecule tool
compounds for academic researchers.
The activities will include establishing and performing primary assays in
screening format with the aim to develop and optimize specific small molecule
probe compounds or profile small molecules for efficacy across cell lines, and
patient models. Activities will also include evaluating different assay
formats, establishing cell-based and biochemical high throughput and high
content screens, working with primary patient cells or complex disease models.
You will be responsible for managing projects in close collaboration with
researchers from diverse backgrounds and delivering high-quality data
Eligible applicants will have a well-documented track record of relevance to
the employment. You have a Ph.D. in a relevant area or equivalent experience
from industry or academic screening lab Previous experience of both
biochemical and cell-based assay development and small-molecule screening from
pharmaceutical industry or academic screening centers is highly merited. You
will need a strong passion for daily experimental work and an aptitude for
analyzing, managing, interpreting and reporting high quality screening data.
Laboratory automation experience and an ability to troubleshoot screening
equipment, including robotic liquid handlers and plate readers will also be
considered valuable. The successful candidate must have a staff scientist mind
set, be service minded and dedicated to high quality and reproducible data
production, have very good interpersonal and cooperation skills, enjoy
collaborative science, be flexible and capable of working independently in a
structured and efficient way. Excellent communication skills in written and
spoken English are essential, as well as documentation skills and experience
with electronic lab notebooks is merited.
What do we offer?
Karolinska Institutet is one of the world's leading medical universities. Our
vision is to pursue the development of knowledge about life and to promote
better health for all. At Karolinska Institutet, we conduct innovative medical
research and provide the largest range of biomedical education in Sweden.
Karolinska Institutet is a state university, which entitles employees to
several benefits such as extended holiday and a generous occupational pension.
Employees also have free access to our modern gym and receive reimbursements
for medical care.
Welcome to apply at the latest 2022-01-16
The application is to be submitted through the Varbi recruitment system.In
this recruitment, you will apply with your CV without a personal letter.
Instead, you will answer some questions about why you are applying for the job
in the application form.
Want to make a difference? Join us and contribute to better health for
|Type of employment
||Temporary position longer than 6 months
|First day of employment
|Number of positions
|Last application date
||16.Jan.2022 11:59 PM CET