RESEARCH TECHNICIAN II

Duke University

United States

February 7, 2022

Description

Duke University and Duke University Health System require all students, faculty and staff to receive the COVID-19 and influenza vaccines. After you have officially accepted a position at Duke, you may request a religious or medical accommodation.

RESEARCH TECHNICIAN II

Requisition Number:: 172708

Date: Jan 7, 2022

Location:

Durham, NC, US, 27710

Personnel Area: MEDICAL CENTER

This Position is Partially Grant Funded

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.

Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

RESEARCH TECHNICIAN II

DHVI - RBL

The Duke Human Vaccine Institute (DHVI), an international leader in the fight against major infectious diseases, is seeking a highly motivated individual for the position of Research Technician II. Investigators at the DHVI conduct basic and translational research to develop novel vaccines, therapeutics and diagnostics for diseases that impact global health such as COVID, influenza, Zika, HIV and malaria.

The Duke Regional Biocontainment Laboratory (RBL) is a division of the DHVI and supports a wide portfolio of research programs that require increased levels of biosecurity and biosafety. The RBL has three collaborative core units, Immunology, Virology, and Microbiology, and an Animal Models support team. The Research Technician II will work in the RBL Animal Models team to perform pre-clinical animal studies to develop the next generation of drugs and vaccines to combat infectious disease of global concern. The position reports to the Duke RBL Research Animal Coordinator.

RESPONSIBILITIES :

  • Perform all tasks associated with in vivo small animal models of treatment/challenge such as dosing, collecting samples and precise harvesting and processing of tissues/biospecimens, in multiple species including, but not limited to, ferrets, hamsters, mice and rabbits.
  • Prepare samples for and perform immunological and virological assays including, but not limited to, pathogen load assessment (PCR, Plaque, Colony assays), antibody and biomarker profiling (Luminex/ELISA) and gene expression (PCR, RNA seq.)
  • General laboratory maintenance including but not limited to: laboratory organization, preparation of solutions, waste processing, ordering/preparation/stocking of consumables and reagents, routine equipment calibration, maintenance of accurate sample and equipment inventories.
  • Coordinate equipment maintenance performed by outside vendors.
  • Attend all required trainings and team meetings.
  • Confer with Research Animal Coordinator / Program Manager for Animal Models / Principal Investigator to review work assignments and develop plans for studies; make minor modifications to existing procedures and techniques to meet the needs of particular studies as required.
  • Manage and complete all assigned tasks/projects in accordance with standardized operating procedures and in full compliance with all safety protocols.

  • Complete and maintain written and electronic documentation of research activities in real time according to standardized record keeping procedures.

  • Collect and organize raw data into reports for interpretation and analysis.

  • Perform additional duties as requested by Research Animal Coordinator and RBL/DHVI leadership.
  • Required Qualifications at this Level

  • Education/Training: Work generally requires a bachelor's degree in biology or other directly related scientific field.
  • Experience: None required beyond above education/training requirement.
  • Additional Requirements and Preferences:

  • Two years of laboratory animal husbandry/handling experience preferred.
  • The successful applicant must be eligible for and willing to:

  • Work with animal models of experimental vaccination and viral challenge handled at ABSL2 and ABSL3.

  • Complete external certification for independent work at Biological Safety Level 3 (BSL3) and animal BSL3 (ABSL3).
  • Work with infectious biological agents (viruses) handled at BSL2 and BSL3.
  • Comply with vaccination requirements.
  • Complete Tier 1 Select Agent registration.
  • Certification with the American Association of Laboratory Animal Science (AALAS) at the ALAT level or higher preferred or gain ALAT certification within 1 yr.
  • Weekend and evening work may be needed occasionally.
  • Able to lift 25 lbs. and reach above head and below knees. Work prolonged periods wearing personal protective equipment.
  • Job Code: 00000951 RESEARCH TECHNICIAN II Job Level: 08

    Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

    Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

    Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

    Nearest Major Market: Durham Nearest Secondary Market: Raleigh

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