Research Technician I - Core Laboratories Center

Weill Cornell Medical College

United States

December 24, 2021


Title: Research Technician I - Core Laboratories Center

Location: Upper East Side

Org Unit: Core Laboratories Center

Work Days: Monday-Friday

Exemption Status: Non-exempt

Position Summary

The Human Immune Monitoring Core (HIMC) at Weill Cornell Medicine in New York City is seeking a highly motivated and talented technician to join our team. The HIMC is an innovation-oriented high-tech service center with state- of-the-art instrumentation for advanced immunology studies. Current technology platforms include Cytek Aurora (high-parametric spectral flow cytometry), CyTOF (high-parametric mass cytometry), Hyperion (high-parametric tissue imaging by mass cytometry), and 10x Genomics (multiomic single-cell analysis, immune profiling, and spatial transcriptomics).

At HIMC, the candidate will have opportunities to work with many renowned scientists and physicians at Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center, Rockefeller University, and other world-renowned institutions in the area, on both basic and translational research projects in cancer biology & immunotherapy, inflammation & autoimmunity, infectious diseases, neuroscience, aging & regenerative medicine, and various other cutting-edge immunology research and technology development projects.

Key responsibilities include: operation, maintenance, and troubleshooting of advanced cytometry and imaging instruments; preparation of samples and reagents; and assistance with assay development and optimization.

Job Responsibilities
  • Prepares and maintains detailed records, logs and summary reports of all procedures and results including graphs, scientific calculations, and statistical analysis charting.
  • May be responsible for tissue & cell culture activities.
  • May be responsible for animal husbandry, genotyping, surgeries, post- operative care, behavioral testing, sectioning and histology.
  • May perform routine molecular biology laboratory procedures, such as PCR, protein and DNA electrophoresis, cloning and DNA preparation.
  • May run routine biochemistry assays including western blotting and RT-PCR.
  • May perform microscopic imaging analyses.
  • May be responsible for the receipt, storage, cataloguing and shipment of samples within and between institutions.
  • Ensures a clean working area and is responsible for washing and storing glassware.
  • Ensures that safe laboratory practices are followed, including the use and disposal of chemicals and hazardous materials.
  • Analyzes data using computer software and reports results to the principle investigator(s).
  • Provides technical support to faculty and staff including training of new employees, residents, postdoctoral associates, fellows and students.
  • Participates in planning and carrying out experiments. Assists in preparing research protocols.
  • Conducts library research and literature searches using various computer systems. Assists in editing scientific publications, abstracts and posters.
  • Maintains inventory of supplies, equipment and/or reagents. May order supplies/equipment/reagents as authorized or ensure that needs are escalated appropriately. Receives supply orders and confirms accuracy of delivery. May assist with cost control.
  • Ensures that facilities and equipment are in optimal and proper working condition. Coordinates preventative maintenance and repairs as needed. May perform minor repairs if qualified and as needed. May advise on upgrades for performance enhancements.
  • Education
  • Bachelor's Degree
  • Experience

    Bachelor's or Master's degree in biological sciences, engineering, chemistry, physics, mathematics, computer science, or related fields.

    Some bench lab/software related experience - familiarity and excellent skills with PCR-clean molecular biology and aseptic techniques; prior experience with cytometry or tissue imaging can be helpful but is not required, as training will be provided; familiarity with Excel or spreadsheet software.

    Minimum two-year commitment due to a substantial training effort associated with the position.

    Other responsibilities include:

  • Operate and maintain the Aurora/FACS, CyTOF/Hyperion, 10x Genomics, and/or other state-of-the-art instruments of HIMC.
  • Prepare and manage reagents. Perform reagent validation, titration, and QC.
  • Process clinical specimens and prepare cells and slides for analysis.
  • Maintain a detailed, up-to-date, and accurate record of samples, reagents, processing notes, and instrument QC log. Organize laboratory inventories and place orders.
  • Perform routine data processing tasks and QC procedures and participate in advanced data analysis projects.
  • Perform other tasks on assay development, sample preparation, data analysis, and user training as assigned by the core director.
  • Contribute to building a culture that embraces scientific excellence, service integrity, efficiency, teamwork, and continuous learning and improvement.

    Knowledge, Skills and Abilities
  • Demonstrated organizational skills and ability to pay close attention to detail.
  • Ability to plan and prioritize work while responding flexibly to rapidly changing priorities.
  • Licenses and Certifications Working Conditions/Physical Demands

    Standard laboratory conditions.

    Ability to work flexible hours.

    This position may handle radioactive material and/or biologic materials from human subjects as required.

    This position may require standing or sitting for long periods of time.

    This role may require working within Biologic Safety Level 1, 2 and/or 3 facilities

    Weill Cornell Medicine is a comprehensive academic medical center that's committed to excellence in patient care, scientific discovery, and the education of future physicians in New York City and around the world. Our doctors and scientists-faculty from Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences, and the Weill Cornell Physician Organization-are engaged in world-class clinical care and cutting-edge research that connect patients to the latest treatment innovations and prevention strategies. Located in the heart of the Upper East Side's scientific corridor, Weill Cornell Medicine's powerful network of collaborators extends to its parent university Cornell University; to Qatar, where an international campus offers a U.S. medical degree; and to programs in Tanzania, Haiti, Brazil, Austria and Turkey. Our medical practices serve communities throughout New York City, and our faculty provide comprehensive care at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, NewYork- Presbyterian/Lower Manhattan Hospital, and NewYork-Presbyterian/Queens. At Weill Cornell Medicine, we work together to treat each individual, not just their conditions or illnesses, as we strive to deliver the finest possible care for our patients - the center of everything we do. Weill Cornell Medicine is an Equal Employment Opportunity Employer. Weill Cornell Medicine provides equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information.

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