Research Associate

University of Glassgow

United Kingdom

November 4, 2021

Description

Research Associate

Job Purpose

The post holder will join the Institute of Infection, Immunity and Inflammation, MRC University of Glasgow Centre for Virus Research (CVR) working with the Principal Investigator, Dr Alfredo Castello and work in an ERC-funded project aiming to discover and characterise the cellular RNA- binding proteins that regulate virus infection. This pioneering research will apply a novel approach to elucidate the interactions that viral RNAs establish with the host cell in a proteome-wide scale. In a second phase, this research will determine which of these host-virus interactions play critical roles in virus infection and will provide mechanistic insights into these regulatory mechanisms. We expect to identify cellular RNA-binding proteins, with master regulatory roles in the viral life cycle that could be exploited as targets for broad-spectrum antiviral treatments. The project will make use of a wide range of viruses and will employ cutting edge technologies, including next generation proteomics and RNA sequencing.

The successful candidate is also expected to contribute to the formulation and submission of research publications and funding proposals as well as to participate in the training and supervision of students in the laboratory.

Main Duties and Responsibilities

1. Take a leading role in the planning and conduct of assigned research individually or jointly in accordance with the project deliverables.

2. Document research output, including analysis and interpretation of data, maintaining records and databases, drafting technical/progress reports and papers as appropriate.

3. Establish and maintain your research profile and reputation and that of the Castello laboratory and CVR, including establishing and sustaining a track record of independent and joint publications of international quality in high profile/quality refereed journals, enhancing the research impact in terms of economic/societal benefit, and gathering indicators of esteem.

4. Survey the research literature and environment, understand the research challenges associated with the project and subject area, and develop/implement a suitable research strategy. Keep up to date with current knowledge and recent advances in the field/discipline.

5. Presentation of work at international and national conferences, at internal and external seminars, colloquia and workshops to develop and enhance our research profile.

6. Take a leading role in the identification of potential funding sources and to assist in the development of proposals to secure funding from internal and external bodies to support future research.

7. Take a leading role in developing, managing and maintaining internal and external collaborations.

8. Take a leading role in team/group meetings/seminars/workshops and Institute research group activities to enhance the wider knowledge, outputs and culture of the CVR.

9. Take the lead in the organisation, supervision, mentoring and training of undergraduate and/or postgraduate students and less experienced members of the project team to ensure their effective development.

10. Generate, manage, document, maintain and store the data generated with the standards described in the project.

11. Perform administrative tasks related to the activities of the project, including Budgets/Expenditure/ordering, and contribute to lab management and general lab duties.

12. Make a leading contribution to Teaching activities (e.g. demonstrating etc) and outreach in consultation with the PI.

13. Engage in personal, professional and career development, to enhance both specialist and transferable skills in accordance with desired career trajectory.

14. Contribute to the enhancement of the University's international profile in line with the University's strategic Plan, World Changers Together.

Please note that as part of your application you must address and demonstrate how you meet EACH of the essential/desirable criteria, point by point.

Qualifications

Essential

A1 Normally Scottish Credit and Qualification Framework level 12 (PhD) in Biochemistry, Molecular Biology or other relevant subject, or alternatively possess the equivalent in professional qualifications and experience, with experience of personal development in a similar or related role(s)

Knowledge and Skills

Essential

C1 Extensive knowledge in RNA biology and RNA biochemistry.

C2 A substantial background in molecular virology.

C3 Knowledge in OMICS approaches for protein and RNA studies.

C4 Excellent team working and collaboration skills.

C5 Excellent communication skills (oral and written).

C6 Appropriate workload/time/project management skills.

C7 Good leadership skills including demonstrable supervisory skills.

Desirable

D1 Knowledge in alphaviruses.

Experience

Essential

E1 Sufficient depth of relevant research experience, normally including sufficient postdoctoral experience in a related field, appropriate to an early career researcher.

E2 Substantial work experience in RNA biology.

E3 Relevant experience in virology.

E4 Experience working with OMIC approaches.

E5 Experience working with cultured human cells.

E6 Experience with fluorescent microscopy.

E7 Experience in scientific writing, including research manuscripts or/and funding applications.

E8 Publications, including at least one as first author, in appropriate-impact international peer-reviewed scientific journals.

Desirable

F1 Experience working with alphaviruses.

F2 Experience with other molecular, cellular and structural biology methods.

Further Enquiries

Informal enquiries may be directed to Dr Alfredo Castello via email Alfredo.Castello@glasgow.ac.uk

This position is available on a full time basis and is funded in first instance until 31 March 2023, with the possibility of further extension.

Terms and Conditions

Salary will be on the University's Research and Teaching Grade 7, £36,382 - £40,927 per annum.

This position is available on a full time basis and is funded in first instance until 31 March 2023, with the possibility of further extension.

New entrants to the University will be required to serve a probationary period of 6 months.

The successful applicant will be eligible to join the Universities' Superannuation Scheme. Further information regarding the scheme is available from the Superannuation Officer, who is also prepared to advise on questions relating to the transfer of Superannuation benefits.

All research and related activities, including grants, donations, clinical trials, contract research, consultancy and commercialisation are required to be managed through the University's relevant processes (e.g. contractual and financial), in accordance with the University Court's policies.

It is the University of Glasgow's mission to foster an inclusive climate, which ensures equality in our working, learning, research and teaching environment.

We strongly endorse the principles of Athena SWAN, including a supportive and flexible working environment, with commitment from all levels of the organisation in promoting gender equality.

Vacancy Reference: 069547, Closing Date: 4 November 2021

Vacancy Ref : 069547 Close Date : 04-Nov-2021 23:45

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