Research Associate (Philpott Lab) (Fixed Term)

University of Cambridge

United Kingdom

October 2, 2022


Research Associate (Philpott Lab) (Fixed Term)

Neuroblastoma is a devastating paediatric cancer of the peripheral nervous system that causes 15% of all children's cancer deaths in the UK each year. Neuroblastoma arises from neuroblasts that fail to complete their normal developmental programme but are instead locked in a state of enhanced proliferation and inhibited differentiation. The goal of the Philpott lab is to exploit an understanding of normal neuroblast developmental control to restart differentiation in neuroblastoma cells by targeting a key transcriptional network both genetically and with drugs.

We are looking for a post-doctoral scientist to join our collaborative research team to probe the molecular regulation of transcriptional networks that control proliferation versus differentiation of neuroblastoma cells. The successful candidate will use genome-wide techniques coupled with molecular analysis to interrogate the transcriptional and epigenetic control of gene pathways regulating proliferation versus differentiation in neuroblastoma cells, with the aim of developing new therapeutic approaches for this terrible disease.

The successful candidate will have a PhD or equivalent experience, considerable experience in stem cell biology, epigenetics, molecular biology, developmental biology or a similar field, and a proven track record in scientific publication. Prior experience in mammalian cell culture is essential. Experience of epigenetics and/or transcriptional regulation are essential, while experience of genome-wide transcriptional analysis and/or CRISPR methods would be an advantage. Applicants must display an ability to undertake project management, work within a multi-disciplinary team environment, have good presentation and communication skills and the ability to contribute to an environment supporting researchers at all stages of their careers.

Our group is housed in the Wellcome-MRC Cambridge Stem Cell Institute, a world-leading centre for stem cell research with the mission to transform human health through a deep understanding of stem cell biology. https: // www.

Please contact Prof. Anna Philpott ( with any informal enquiries.

Fixed-term: The funds for this post are available until 30 September 2024 in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Closing Date: 2 October 2022

Interview Date: TBC

Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager.

Please quote reference PS33145 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information
  • Further Particulars
  • Department/Location

    Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute








    13 September 2022

    Closing date

    2 October 2022

    Similar Jobs

    University of Cambridge

    United Kingdom 13 hours ago

    Add to favorites

    Research Laboratory Technician (Fixed Term)

    Research Laboratory Technician (Fixed Term) Cambridge Stem Cell Institute (CSCI) and the Department of Paediatrics, Current research themes of the group include the The post-holder will have an interest in CNS glial cell development and...

    University of Cambridge

    United Kingdom 13 hours ago

    Add to favorites

    Research Associate (Karadottir Lab) (Fixed Term)

    Research Associate (Karadottir Lab) (Fixed Term) The Wellcome Trust Medical Research Council Stem Cell Institute draws together outstanding researchers from 29 stem cell laboratories in Cambridge to form a biology of stem cells and provide...

    University of Oxford

    United Kingdom 1 day ago

    Add to favorites

    Postdoctoral Research Associate in Cohesion Establishment in Mammalian Cells

    Postdoctoral Research Associate in Cohesion Establishment in Mammalian Department of Biochemistry, South Parks Road, Oxford Chromosomal Biology research group of Dr. Madhusudhan Srinivasan and Professor in core molecular and cell biology techniques, such as cloning,...

    University of York

    United Kingdom Sep 2, 2022

    Add to favorites

    Research Associate in Haematology/Cancer Biology

    Research Associate in Haematology/Cancer Biology Role Description Department Associates to join the group of Professor Ian Hitchcock based in the Department of Biology at the University of York. understanding the mechanisms of cytokine signalling in...

    Add to favorites


    Research Field: Biological sciences › Biology Location: Greece › Heraklion The mitotic spindle is a microtubule-based apparatus that is responsible Defects in spindle formation can novel phosphorylation sites on tubulin, which are essential for optimal...

    University of Oxford

    United Kingdom Sep 8, 2022

    Add to favorites

    Postdoctoral Research Assistant

    Sciences, Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, We are looking a talented Postdoctoral Research Assistant to join the group of Associate Professor Tal Arnon at the Kennedy Institute, the University of regulate humoral immunity...