Research Associate - Laurenti Lab (Fixed-term)

University of Cambridge

United Kingdom

September 26, 2022

Description

Research Associate - Laurenti Lab (Fixed-term)

Applications are invited for the positions of Research Associate to join the group of Dr Elisa Laurenti within The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute and Department of Haematology on the Cambridge Biomedical Campus. This project will focus on understanding the heterogeneity of behaviours of human blood stem cells and their relevance to blood formation and human health. In recent years, work from many groups, including that of Dr Laurenti, has shown that there are different blood stem cell subtypes. Some of these subtypes are "atypical" because they do not possess all of the classical features of a blood stem cell. Specifically, this Wellcome sponsored project will study how these "atypical" blood stem cells are formed and to what extent they contribute to stress responses. The project will predominantly use single cell technologies (functional assays and single cell -omics) on primary patient samples. Key biological questions will centre around the molecular regulation of lineage decisions under healthy, stressed and diseased conditions.

Candidates should hold a PhD in a relevant field. In particular, they will have a strong background either in stem cell biology or haematology. Extensive experience (ideally more than 3 years) with flow cytometry and tissue culture is required. The candidate should also possess some experience with single cell -omics technologies. Additional expertise of mouse models and/or of high-throughput sequencing data analysis would be desirable. Finally, they will have demonstrated a strong scientific achievement via their publication record.

The post holder is expected to creatively and independently carry out their own research project, while collaborating on a regular basis with a team of experimentalists and computational biologists. They will also effectively communicate their work in writing and oral presentations at internal meetings and international conferences.

Questions regarding the post can be directed to Dr Elisa Laurenti who can be contacted at el422@cam.ac.uk.

Fixed-term: The funds for this post are available until 13 June 2024 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Closing date: 26th September 2022

Interview date: 4th and/or 5th of October 2022.

Please quote reference PS32851 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information
  • Further Particulars
  • Department/Location

    Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute

    Salary

    £33,309-£40,927

    Reference

    PS32851

    Category

    Research

    Published

    23 August 2022

    Closing date

    26 September 2022

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