Research Associate (Fixed Term)
Applications are invited for a Research Associate to join the group of Dr Matt
Hoare within the new Early Cancer Institute on the Cambridge Biomedical
Campus. Our group is interested in why patients with chronic liver disease
develop liver cancer. This is an exciting opportunity to join a CRUK-funded
5-year project, based on previous findings from the group (Brunner et al,
Nature, 2019; Ng et al, Nature, 2021) and will further define how acquired
somatic mutations impact on cell survival, liver cancer development and
systemic metabolic dysfunction.
We are seeking to hire a motivated post-doctoral Research Associate with a
background in cancer research and mouse work to join the team. The successful
candidate will join a pioneering research project investigating functional
mechanisms and downstream consequences of somatic mutagenesis in the liver
and, in particular, two recurrently mutated genes in chronic liver disease. To
deliver this project the successful candidate will use a variety of in vitro
and in vivo techniques, particularly novel mouse models of these acquired
hepatocyte mutations. The successful candidate will join a successful and
collaborative group in a new institute focussed on cancer early detection. In
this post you will have the opportunity to develop your career, through
cutting-edge research, interactions with great collaborators in the UK, Europe
and the US and be placed on one of the largest biomedicine clusters in the UK.
Applicants should hold a PhD in cancer, metabolism or liver biology, or be
close to the completion of their degree. Candidates that have a strong
background any of the following three broad areas of expertise are encouraged
to apply: (1) mouse models of cancer or liver disorders; (2) organoid
derivation, culture and manipulation, or (3) single-cell multi-omics and
epigenomics. Prospective candidates are encouraged to contact Dr Hoare
(firstname.lastname@example.org) directly when considering an application to discuss the
project in greater detail.
Fixed-term: The funds for this post are available for 5 years in the first
Click the 'Apply' button below to register an account with our recruitment
system (if you have not already) and apply online.
Appointment at Research Associate level is dependent on having a PhD. Those
who have submitted but not yet received their PhD will initially be appointed
as a Research Assistant (Grade 5, Point 38 £30,497) moving to Research
Associate (Grade 7) upon confirmation of your PhD award. Please ensure that
you upload a covering letter and CV in the Upload section of the online
application. The covering letter should outline how you match the criteria for
the post and why you are applying for this role. If you upload any additional
documents which have not been requested, we will not be able to consider these
as part of your application. Please include details of your referees,
including email address and phone number, one of which must be your most
recent line manager.
Please quote reference RD33224 on your application and in any correspondence
about this vacancy.
The University actively supports equality, diversity and inclusion and
encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible
to live and work in the UK.
Department of Oncology, Cambridge
16 September 2022
17 October 2022