Research Assistant/Research Associate (Fixed Term)
The Sawarkar lab at the MRC Toxicology Unit is looking to appoint a
Postdoctoral Molecular Cell Biology Scientist to contribute to its programme
on Epigenetics, Neurodegeneration and Protein Misfolding.
The project will use state-of-the-art genomic technologies to identify
epigenetic determinants that lead to protein misfolding in neurons. Using
single-cell technologies for in vivo mouse models as well as embryonic stem
cell differentiation models of neurodegeneration, the project will identify
mechanisms leading to age-associated protein misfolding in neurons.
Your role will be to support the research activities of the group and conduct
your own research projects within the remit of the research programme at the
frontiers of molecular bioscience.
You will need to hold, or be close to completing, a PhD in a degree in an
appropriate field (e.g. in vivo biology or physiology), together with hands-
on experience in routine molecular cell biology techniques. You will be able
to work both independently and as part of a team, have excellent
communication, organisational and problem-solving skills and ideally have
experience of working on an independent research project. Enthusiasm for
working in a diverse inter-disciplinary team is desirable.
The MRC Toxicology Unit is an internationally renowned institution focused on
the delivery of field-changing mechanistic insights into toxicology and
disease. The Unit is equipped with state-of-the-art facilities including mass
spectrometry, microscopy, and bioinformatics, and offers excellent
opportunities for scientific career development.
Appointment at Research Associate is dependent on having a PhD. Where a PhD
has yet to be awarded or submitted, appointment will initially be made as a
Research Assistant and amended to Research Associate when the PhD is awarded.
Further information on the Toxicology Unit can be found at (https: // www. mrc-
Rawat P, Boehning M, Hummel B, Aprile-Garcia F, Pandit AS, Eisenhardt N, Khavaran A, Niskanen E, Vos SM, Palvimo JJ, Pichler A, Cramer P, Sawarkar R. (2021) Stress-induced nuclear condensation of NELF drives transcriptional downregulation. Mol Cell. doi: 10.1016/j.molcel.2021.01.016.
Antonova A, Hummel B, Khavaran A, Redhaber D, Aprile Garcia F, Rawat P, Gundel K, Schneck M, Hansen E, Mitschke J, Mittler G, Miething C and Sawarkar R (2019) Heat-shock protein 90 controls the expression of cell-cycle genes by stabilizing metazoan-specific Host-Cell Factor HCFC1. Cell Reports. 29(6):1645-1659.e9.
Fixed-term: This post is funded by the ERC for three years in the first
instance, with the possibility of an extension of up to four years.
Click the 'Apply' button below to register an account with our recruitment
system (if you have not already) and apply online.
Enquiries can be sent to Ritwick Sawarkar firstname.lastname@example.org
Please quote reference PU31686 on your application and in any correspondence
about this vacancy.
The University actively supports equality, diversity and inclusion and
encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible
to live and work in the UK.
Ritwick Research Associate ERC
MRC Toxicology Unit, Cambridge
£27,116 - £31,406
or £33,309 - £40,927
8 June 2022
10 July 2022