The Synthetic RNA Biology Lab at the Department of Biology invites
applications for the position of a
Research Assistant (PhD Studentship) – 65%
for a funding period of three years initially.
Our research focuses on regulatory RNA structures. One of our key topics is
viral replication, in particular the characterization of RNA-ligand
The aim of the project "Target-RNAantiV" is the development of novel small
molecule inhibitors against essential regulatory RNA elements in the genome of
SARS-CoV-2. RNA structures in the genome of SARS-CoV-2 are crucial for viral
replication and therefore potential drug targets. Especially, RNA structures
that control the translation of viral proteins will be investigated.
The project includes FACS-based high-throughput screening, toxicity assays,
and genome editing by CRISPR/Cas in BSL1 cell culture. Active collaboration
with structural biology and pharmaceutical/medical groups is expected.
Successful applicants will work in an exciting and interactive research
environment as members of a dynamic team of international scientists and apply
the latest technologies in biochemistry and molecular biology. The projects
are embedded in an international consortium “COVID19-NMR” as well as the CRC
902 “Molecular Principles of RNA-based Regulation”. Association to both the
international community of the consortium and the integrated graduate school
of the CRC guarantees an excellent collaborative and interdisciplinary
environment for research and a well-structured training in scientific and
other key competences.
The prerequisite for employment is a completed degree (Master of Science or
comparable) in life sciences or related natural sciences with excellent
grades. You have practical experience in the field of biochemistry and/or
molecular biology and have a keen interest in experimental research. We expect
highly motivated students who enjoy working in a team. Excellent English
language skills are essential.
Opportunity for further qualification (doctoral dissertation) is given. The
fulfillment of the duties likewise enables the scientific qualifications of
The Technische Universität Darmstadt intends to increase the number of female
employees and encourages female candidates to apply. In case of equal
qualifications applicants with a degree of disability of at least 50 or equal
will be given preference. Wages and salaries are according to the collective
agreements on salary scales, which apply to the Technische Universität
Darmstadt (TV-TU Darmstadt).
Applications (in german or english) including the standard documents, the
abstract of the Master's thesis and the contact details of the supervisor of
the Master's thesis should be sent in electronic form (as a single pdf)
giving the identification number to: firstname.lastname@example.org
By submitting your application, you agree that your data may be stored and
processed for the purpose of filling the vacancy. You can find our privacy
policy on our webpage.
Code No. 403
July 19, 2021
August 02, 2021