Research Assistant neuronal cell biologist: “Novel therapeutic targets in neuronal models of Parkinson’s disease”

University of Oxford
November 28, 2023
Offerd Salary:Negotiation
Working address:N/A
Contract Type:Fixed-term until 31
Working Time:Full time
Working type:N/A
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Research Assistant neuronal cell biologist: “Novel therapeutic targets in neuronal models of Parkinson's disease”

Kavli Institute for Nanoscience Discovery, South Parks Road, Oxford, OX1 3PT

Full-time, Fixed-term until 31 December 2024

Applications are invited for a Research Assistant neuronal cell biologist to work on a project developing disease-modifying therapies in patient stem cell- derived neuronal models of Parkinson's. The project, in collaboration with EndLyz, a new company within the Dementia Discovery Fund (DDF) portfolio, represents an exciting opportunity to undertake translation work at the interface between academic research and pharmaceutical target and drug discovery in an exceptional setting. This work will develop novel therapies for Parkinson's by better understanding the cellular and molecular mechanisms through working with induced pluripotent stem cell (iPSC)-derived dopamine neurons generated from Parkinson's patients.

Duties will include undertaking laboratory experiments; interpretation of data; imaging analysis; generation and study of iPSC-derived neurons and cell lines; preparation of data for publication; study the mechanisms of action of modulators of the endolysosomal pathway in cellular models of Parkinson's; contribute to wider project planning and determine the most appropriate methodologies to test hypotheses. You will have excellent practical experience of working with induced pluripotent stem cell cultures and good knowledge of cellular models of neurodegenerative disease. The ability to innovate, trouble-shoot technical problems, be meticulous in practical work and in record keeping is essential.

Applicants must hold, or be near completion of, a BSc/MSc in a relevant area of research and have experience in cellular neuroscience or molecular cell biology relevant to analysis of neuronal phenotypes.

The post is available for 12 months to start on January 1st 2024. The post will be based in the Laboratory of Molecular Neurodegeneration, Kavli Institute for Nanoscience Discovery, South Parks Road, Oxford.

Informal enquiries may be directed Professor Richard Wade-Martins ([email protected]).

Closing date for applications is midday on 28 November 2023.

Interviews are likely to be held on the week beginning 4th December 2023.

Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.

While this is a full-time role, we welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.

We, as a Department and Community, will be considerate and welcoming of all people, regardless of race, ethnicity, religion, disability, sexual orientation and gender identity. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. – DPAG Statement of Inclusion

Contact Person : HR Team Vacancy ID : 169116 Contact Phone : 01865282167 Closing Date & Time : 28-Nov-2023 12:00 Pay Scale : STANDARD GRADE 6 Contact Email : [email protected] Salary (£) : 32332 - 38205

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