Research Area Specialist Assoc

University of Michigan

United States

July 12, 2021


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Job Summary

The Paulson/Sharkey laboratories are looking for a Research Area Specialist Associate skilled in molecular biology, biochemistry and proteomic techniques. The overarching goals of the laboratory are to 1) understand the mechanisms that regulate protein homeostasis in neurons and 2) to determine why deficits in these pathways lead to protein misfolding/aggregation and neurotoxicity. We study these pathways with the goal of developing potential treatments for neurodegenerative diseases such as Alzheimer's Disease, amyotrophic lateral sclerosis and frontotemporal dementia. Specifically, the successful candidate will work alongside Dr. Paulson, Dr. Sharkey and existing lab members to design, perform, and interpret experiments focused on the ubiquilin family of proteins and their role in protein quality control in the cell. In addition, they will supervise and help train both undergraduate research assistant as well as junior technicians in the lab.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world's most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

  • Excellent medical, dental and vision coverage effective on your very first day
  • 2:1 Match on retirement savings
  • Responsibilities

    Responsibilities include but are not limited to:

  • Laboratory maintenance

  • Conduct experiments

  • Analyze data

  • Train users in equipment operation and standard techniques

  • Participate in periodic research discussions

  • Present data and plans for new experiments

  • Collaborate with colleagues to achieve short and long range plans

  • Help assemble manuscripts, chapters and research abstracts

  • Additional duties as assigned

  • Required Qualifications

    Requirements include a masters degree in the biological sciences, including molecular biology, biochemistry or a related discipline and 1-2 years of laboratory experience which could include classroom laboratory experience or employment.

    Candidates will be expected to actively take part in collaborations. Applicants should be reliable and able to work well within a group. Preference will be given to applicants who seek more than 1-2 years of commitment to this position.

    Desired Qualifications

    Familiarity with basic techniques in biomedical research including mammalian and primary cell culture, DNA/RNA extraction and purification, quantitative real-time PCR, Western blotting, and fluorescence microscopy. Experience with mouse colony husbandry, genotyping, and tissue dissection and analysis is also desirable.

    Background Screening

    Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre- employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

    U-M EEO/AA Statement

    The University of Michigan is an equal opportunity/affirmative action employer.