Reference Number SLSC1131 - Cell-Based Assay Development Scientist

University of Dundee

United Kingdom

September 27, 2022

Description

Reference Number SLSC1131

Job Title Cell-Based Assay Development Scientist College/SASS School of Life Sciences School/Directorate Biological Chemistry and Drug Discovery Grade ZZDNU(2021) Grade 7 (£33,309 - £40,927) Job Category Research Closing Date 27 September 2022

The Drug Discovery Unit (DDU) at the University of Dundee is globally recognised for its scientific excellence and delivery of new candidate drugs for infectious diseases. The DDU comprises over 130 highly skilled and motivated staff, spanning all core drug discovery disciplines and is equipped with state-of-the-art facilities.

We have an exciting opening for a cell-based assay development scientist to set up a suite of assays for the pathogenic fungus Cryptococcus neoformans. Within the DDU we have extensive expertise in building cascades of cell-based assays that combine the high-throughput required to screening large compound collections with the physiological relevance required to progress compounds with confidence. We are now expanding our portfolio to include cryptococcosis and seek to develop a fit-for-purpose screening cascade as we have done in the past for kinetoplastid parasites.

This position would be an excellent postdoctoral opportunity to gain expertise in drug discovery but is equally suited to experienced drug discovery assay development scientists.

Who we're looking for:

Who we're looking for:

Essential requirements for the post:

  • A PhD in cell or molecular biology or equivalent experience
  • Experience working with yeast, including culturing on solid media and in liquid media
  • A desire to build robust and reproducible cell-based assays to enable drug discovery
  • Strong interpersonal, communication and presentation skills
  • Ability to be proactive, productive and to work effectively in a team
  • Desirable attributes (not essential, training will be given as needed):
  • Experience in:

  • Culturing Cryptococcus neoformans
  • Fluorescence microscopy
  • Assay development (for viability assays) and assessment criteria for assay quality and robustness
  • This post is being offered within Grade 7 of our pay scale (point 29 £34,308 – to point 33 £38,592) for two years initially, with an anticipated start date of no later than 16 January 2023 and comes with many excellent employee benefits as outlined here: https: // www. dundee.ac.uk/work-for-us/employee- benefits.

    Commitment to DORA

    The School of Life Sciences has been fully committed to the principals of the San Francisco Declaration on Research Assessment (DORA) since 2013. In assessing applicants, we consider the scientific quality of their published research papers, but do not take into account where the papers were published and do not consider journal-based metrics, such as Journal Impact Factors

    As an internationally diverse institution, we welcome job applicants from all countries and nationalities. The School of Life Sciences is proud to employ staff from over 40 different nations.

    Find out more about 'Working for the University of Dundee'

    For informal discussion about the post please contact Dr Manu De Rycker (m.derycker@dundee.ac.uk) (Please do not send applications to this email address).

    The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena swan, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.

    The closing date for applications is 27 September 2022.

    More Info... SLSC1131 Job Description.docx Click here to apply for this job

    About the employer

    The University of Dundee is a public research institution that was established in the year 1881. The institution served as a constituent body of the University of St Andrews for many years of early existence. It followed significant expansion later...