Postdoctoral Scholar – Research Associate
Apply Keck School of Medicine Los Angeles, California
The USC Roski Eye Institute, Department of Ophthalmology is seeking a
Postdoctoral Scholar-Research Associate to join its team.
We seek a motivated post-doctoral fellow to join our non-viral gene delivery
system in retina for photoreceptor therapeutics project. Candidates are
expected to have knowledge and experience in ultrasound technology, ocular
imaging, molecular biology techniques (e.g., transfection, Crispr/Cas9), and
in vivo experimentation and design. The project focus is the development of
microbubble (MB)-assisted sonoporation method to deliver the Crispr/Cas9
into the eye for the treatment of debilitating hereditary retinal diseases.
Project involves developmental sonoporation system and Crispr/Cas9 plasmid.
Job Summary :
The post-doctoral fellow serves as a research trainee for the purpose of
enhancing and developing research competencies. Participates in planning,
designing and conducting highly technical and complex research projects under
the direction of a supervisor. May or may not work independently. Analyzes
research data and provides interpretations. Contributes to the development of
research documentation for publication and/or prepares technical reports,
papers and/or records.
Responsibilities and Duties
Investigate ultrasound guided microbubble-assisted approach to delivering
Crispr/Cas9 in the eye.
Build and optimize sonoporation system.
Develop imaging modes and techniques for integration of sonoporation.
Design experiments, analyze data, and recommend enhancements to imaging
Design and clone Crispr/Cas9 plasmid for gene therapy of ocular diseases.
Work cross-functionally with biology leads to improve process efficiency
and ensure a functional and safe working environment.
Possess a PhD or be close to the completion of a PhD or DPhil in
Biomedical engineer or relevant field
Background and work knowledge in ultrasound transducer, device, algorithms
Routine molecular biology techniques include cell culture, cloning,
isolation and purification of genomic and plasmid DNA is required.
Skills in programming languages is a plus
Experience in in vivo experiments is a plus.
(Temporary, fixed-term; one year and renewable on the recommendation of the
faculty mentor and at the discretion of the dean. May be renewed up to a
maximum of five years.)
Applicant Attachments (Required): Application/Resume
Applicant Attachments (Optional): Cover Letter
Work Location: HC4 - Estelle Doheny Eye Institute
Percentage of Time: 100%; 37.5 hours
Minimum Education: Ph.D. or equivalent doctorate within previous five years
Minimum Experience: 0-1 year Minimum Field of Expertise: Directly related
education in research specialization with advanced knowledge of equipment,
procedures and analysis methods.
REQ20106657 Posted Date: 10/07/2021 - Thru date - 2022-01-08 Apply