Postdoctoral Researcher in Innate Immunity and Inflammation

University of Oxford

United Kingdom

September 26, 2022

Description

Postdoctoral Researcher in Innate Immunity and Inflammation

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, Oxford OX3 7FY.

We are seeking a highly motivated, academically excellent and proactive Postdoctoral Researcher with a strong background in innate immunity to join the Genomics of Inflammation group of Professor Irina Udalova at the University of Oxford.

You will be carrying out research on the transcriptional and molecular control of inflammatory and immunometabolic diseases, within a leading-edge international consortium (Oxford-Copenhagen-Stockholm) funded by Novo Nordisk Foundation. You will be using advanced immunological and imaging approaches and innovative single cell genomic technologies to study how development and function of innate immune cells, such as neutrophils, monocytes and macrophages, is guided by intrinsic molecular regulators and influenced by extrinsic protein, lipid and metabolic signals. You will benefit from a portfolio of mechanistically-informed immuno-metabolic targets built by our consortium and the unique in vivo models to test cell-specific changes in disease pathogenethis.

You will join an interdisciplinary and international team of scientists and clinician researchers studying the contribution of the immune system in the pathogenesis of immunometabolic diseases. You will be based at the Kennedy Institute of Rheumatology, University of Oxford, which is a world-leading research centre where discovery research drives development of transformative therapies for chronic inflammatory and degenerative disease. You will have an opportunity to visit other research institutes of the consortium.

You will take responsibility for the planning and execution of high quality research, ensuring the validity and reliability of data at all times, co- oridnate multiple aspects of work to meet deadlines and use specialist scientific equipment in a laboratory environment.

You will hold a PhD (or near completion) in immunology, molecular and cellular biology, or similar. You will demonstrate capacity to deliver high quality research outputs, illustrated by a strong publication record in high profile immunological journals. Expertise in neutrophil and/or macrophage biology, in vivo models of intestinal inflammation, spatial single cell and functional genomics approaches and CRISPR/Cas9 knock-out technology would be desirable.

This is a full-time appointment fixed-term for 2 years, the post holder needs to be in place by 01/01/2023.

Due to the nature of the research at the Kennedy Institute of Rheumatology, this job will require additional security pre-employment checks:

• A satisfactory basic Disclosure and Barring Service check

• University security screening (eg identity checks)

You will be required to upload a supporting statement, CV and names of referees as part of your online application.

Contact Person : NDORMS Recruitment Team Vacancy ID : 160350 Contact Phone : Closing Date & Time : 26-Sep-2022 12:00 Pay Scale : STANDARD GRADE 7 Contact Email : hr@ndorms.ox.ac.uk Salary (£) : 33309 - 40927

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The University of Oxford is the oldest university in the English-speaking world, and is actually so ancient that its founding date is unknown – though it is thought that teaching took place there as early as the 11th century. It’s...