Postdoctoral Researcher in in vivo alpha-Synuclein studies

Karolinska Institute Stockholm

Sweden

September 17, 2021

Description

Do you want to contribute to top quality medical research?

The Svenningsson lab is a translational and multidisciplinary research group studying movement disorders, particularly Parkinson's disease, and depression. We use cellular and animal models and analyze samples and biopsies from patients. Our goals are to understand the molecular mechanisms underlying disease states, and to identify novel biomarkers and medically relevant therapeutic targets. At the clinic, we do longitudinal studies on cohorts of patients with Parkinson's disease and other movement disorders, assessing both motor and non-motor symptoms. We also perform clinical trials with novel pharmacological therapies.

Your mission

We are looking for a highly motivated postdoc, with an interest in translational Neuroscience and a strong background in animal models, neuroscience, pharmacology and/or behavioural studies to be involved in one or more projects investigating the molecular mechanisms underlying the alpha- synuclein-mediated neurodegeneration.

Find some of our recent papers here.

The postdoc will use transgenic animal models and viral vector approaches of alpha-synuclein and related molecules for studying alpha-synuclein spread and neurodegeneration caused.

We expect the successful candidate to be able to significantly contribute to the planning and management of their project(s), as well as to the writing of manuscripts and navigation of the peer-review process.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

Requirements:

  • PhD degree in relevant field (i.e. Neuroscience, biochemistry or molecular biology) – preferably graduated within the past 2 years
  • Lead author in at least 2 peer-reviewed publications
  • Documented experience in animal model research techniques (e.g. motor, cognitive and affective behavior tests)
  • Documented experience in animal surgery methods, such as stereotactic surgery, intracerebral injections, transcardial perfusions, etc.
  • Extensive experience in data analysis and data presentation
  • High level of self-motivation and independency
  • Work well with others in a team
  • Willingness to supervise or share experience with students
  • Very good command of written and spoken English
  • Desirable knowledge and experience:

  • Background in behavioural, pharmacological and/or biochemical studies of neuropathology of Parkinson's disease or neurodegenerative disorders
  • Histology methods and Fluorescent and confocal Microscopy
  • What do we offer?

    Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

    Location: Solna

    Read more about the Department of Clinical Neuroscience

    Read more about the research group you will be part of

    Application

    An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)
  • Welcome to apply at the latest September 17, 2021.

    The application is to be submitted through the Varbi recruitment system.

    Want to make a difference? Join us and contribute to better health for

    all!

    Type of employment Temporary position longer than 6 months
    Contract type Full time
    First day of employment According to agreement
    Salary Monthly salary
    Number of positions 1
    Working hours 100%
    City Stockholm
    County Stockholms län
    Country Sweden
    Reference number STÖD 2-3695/2021
    Contact
    • Vendela Breeze, HR-administrator, +46 8-524 832 82, vendela.breeze@ki.se
    • Per Svenningsson, Professor/senior physician, per.svenningsson@ki.se
    Union representative
    • Venus Azhary, OFR, +46 707124127
    • Henry Wölling, SEKO, henry.wolling@ki.se
    • Arsalan Amir, SACO, +46 704831165
    Published 30.Aug.2021
    Last application date 17.Sep.2021 11:59 PM CEST