Postdoctoral Researcher in COVID-19 Vaccine Immune Genetics

University of Oxford

United Kingdom

November 1, 2021


Postdoctoral Researcher in COVID-19 Vaccine Immune Genetics

Nuffield Department of Medicine, Wellcome Centre for Human Genetics, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7BN Grade 7: Salary in range £33,309 - £40,927 per annum

We are seeking a motivated and enthusiastic Postdoctoral Researcher in COVID-19 Vaccine Immune Genetics within Wellcome Centre for Human Genetics There is an urgent need to identify individuals who have, or are at risk of mounting, a low response to COVID-19 vaccination, to determine the underlying heritable, molecular and immunological mechanisms, and to use this knowledge to assess if booster dose vaccination can mitigate a dampened immune response and who should receive such boosters.

You would be joining a multi-disciplinary team that aims to help address this challenge through the recently funded COvid-19 Vaccine Immune Genetics (COVIG) study ‘An immunogenetic approach to guide the need for booster shots and combat immune failure in SARS-CoV-2 vaccine response' led by the University of Oxford. Your work will focus on identifying human genetic and epigenetic determinants of variation in vaccine response. This will help inform identification of individuals and populations who are at risk of mounting a low immune response to COVID-19 vaccination. You will map the immune response to vaccination as a quantitative trait using genome-wide genetic markers and apply next generation sequencing approaches to identify rare genetic determinants of vaccine response.

It is essential that you hold a PhD/DPhil in genetics, bioinformatics, mathematics, computer science or a related field. You will have research experience in statistical genetics and/or bioinformatics. You will have excellent analytical and quantitative skills with a proven ability to think critically about scientific analysis in order to ensure robust results. Previous experience of, and demonstrated competence in, scientific computing using at least one programming language will also be required.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

This position is offered full time on a fixed term contract until 31 August 2022, and is funded by the MRC. Only applications received before 12 midday on 1 November 2021 will be considered. Please quote 153349 on all correspondence.

Contact Person : Phillippa Wall Vacancy ID : 153349 Contact Phone : 01865 617971 Closing Date & Time : 01-Nov-2021 12:00 Contact Email :