Postdoctoral Research Scholar (Translational Research in Pain)

North Carolina State University

United States

July 11, 2021


Posting Details Posting Number PG190453PD

Position Number 00108580 Position Type Post Doc FLSA

Department ID 195001 - Dept of Clinical Sciences

Department 195001 - Dept of Clinical Sciences Job City & State Raleigh, NC

Position Information

Essential Job Duties

The Department of Clinical Sciences is dedicated to excellence in educating and training veterinarians and comparative biomedical scientists, furthering health care and wellness through discovery and clinical research, providing outstanding and compassionate medical care to a diverse range of animal patients, effectively engaging the animal-owning public, government and industry partners, and providing leadership in integrating biomedical sciences to advance One Health. North Carolina State University's College of Veterinary Medicine (CVM) is a dynamic community whose members are dedicated to preparing veterinarians and veterinarian scientists while advancing animal and human health from the cellular level through entire ecosystems.

The college is committed to practicing inclusivity, making community a priority and promoting innovation. We embrace effective leadership and we champion personal and professional growth.

Duties & Responsibilities: The Translational Research in Pain (TRiP) Program is a translational and basic pain research lab at North Carolina State University that studies both: (1) mechanisms of musculoskeletal pain, and (2) therapeutics for musculoskeletal pain. A postdoctoral research scholar position is immediately available. This 4/5-yr project involves work with 3 species (mouse, rat and dog). The work is centered on understanding the utility of targeting VEGF receptors for the management of osteoarthritis and osteoarthritis pain. Our central hypothesis is that targeting both VEGF-1 and VEGF-2 simultaneously elicits dual function: (i) immediate symptom alleviation and (ii) inhibition of cartilage tissue degeneration. Thus, both disease progression and pain are halted. This hypothesis will be rigorously tested using: 1) Different types of target inhibitors – mAbs and small molecules; 2) Two different mouse and rat OA models, and two different dog OA models (including client-owned pet dogs with osteoarthritis). The project involves behavioral assays of pain, function and movement in all species; benchtop molecular biology assays (e.g., qPCR, Western blot, immunohistochemistry, Ca2+ imaging, in-situ hybridization); histology. This will be a two-year minimum position. Our group has strong connections and collaborations with pain researchers at UNC Chapel Hill and Duke University. The selected candidate will work under the direct guidance of Dr. Duncan Lascelles, a translational pain researcher, veterinarian and Specialist in Small Animal Surgery. The selected candidate will work with a technician dedicated to the project. Other team members include 2-3 graduate students; 2 Veterinarian Research Assistants; 2 Research Specialist Technicians; undergraduate students. Close on-site faculty collaborators include Drs. Santosh Mishra (neurobiologist and itch researcher with particular expertise in mouse modeling), Margaret Gruen (veterinarian, Specialist in Behavior, pain researcher) and Mike Nolan (Radiation Oncologist and cancer/pain researcher). We hope you will consider joining us! The postdoctoral associate will be expected to carry out independent work, make presentations regarding his/her research, to publish their research results in peer-reviewed journals, to participate in grant proposal preparation, and to interact with other faculty, postdoctoral associates, and graduate students at the University level and across collaborating institutions of the project. All aspects of work will be closely mentored with the goal of transitioning the incumbent to be an independently funded researcher in the area of pain.

Other Work/Responsibilities

Some Laboratory Manager duties (organizing lab meetings; ordering; equipment repair and maintenance)

Work Schedule Variable but typically M-F 8 hours/day

Department Required Skills

Strong interpersonal skills; strong organizational skills; strong communication skills; strong work ethic. Experience with basic benchtop molecular biology assays (e.g., qPCR, Western blot, immunohistochemistry) Experience with behavioral assays in mice and rats

Preferred Years Experience, Skills, Training, Education

Experience working with dogs preferred Previous grant writing experience preferred Experience in behavioral pain research. Experience in molecular pain research.

Required License or Certification


Valid NC Driver's License required? No Commercial Driver's License Required? No

Recruitment Anticipated Hiring Range $55,000 - $60,000

If you anticipate multiple hires from this search, please indicate how many

Job Open Date 06/10/2021 Quick Link https: //


NC State University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, gender identity, age, sexual orientation, genetic information, status as an individual with a disability, or status as a protected veteran.

If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or Individuals with disabilities requiring disability-related accommodations in the application and interview process, please call 919-515-3148.

Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. If highest degree is from an institution outside of the U.S., final candidates are required to have their degree equivalency verified at www. or equivalent service. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.

NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.

Supplemental Questions

Required fields are indicated with an asterisk ().

  • How did you learn of this opportunity?
  • NCSU Website
  • NCSU Executive Search Services
  • Other Online Job Board
  • Carolina Job Finder / Employment Guide
  • Job / Career Fair
  • The Chronicle of Higher Education
  • HERC
  • Professional Journal
  • Print Advertisement (Newspaper / Periodical)
  • Professional Organization
  • Direct Contact from NCSU HR Representative / Recruiter
  • NCSU Employee Referral
  • Social Media (LinkedIn, Twitter, Facebook, Other)
  • Other
  • If you learned about this vacancy from "other source" or "other website", please provide the source.
  • (Open Ended Question)

    Applicant Documents

    Required Documents

  • Cover Letter
  • Curriculum Vitae
  • Contact Information for References
  • Optional Documents

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