Postdoctoral Research Associate

University of Cambridge

United Kingdom

September 30, 2022

Description

Postdoctoral Research Associate

A position is open for a Postdoc Research Associate in Control of meiotic recombination in Arabidopsis, in the Henderson Group in the Department of Plant Sciences.

Meiotic recombination is a major mechanism that creates genetic diversity in plants and animals and remains a vital tool during crop breeding. This project will explore molecular mechanisms that control the number and distribution of recombination events (crossovers) genome-wide in the model plant Arabidopsis thaliana. We have identified recombination factors (e.g. HEI10) and epigenetic marks (e.g. DNA methylation) that regulate crossover formation in plants (Ziolkowski et al; Yelina et al). In this project, the successful candidate will use molecular genetics and genomics approaches to further understand the control of recombination patterns in the Arabidopsis genome. We have recently used long-read DNA sequencing to complete assembly of the Arabidopsis centromeres (Naish et al). The candidate will explore new ways of using long-read sequencing to study recombination.

The successful candidate will work in the Henderson group to further explore and characterise the genetic and epigenetic control of recombination in Arabidopsis. The scope of the project is flexible, depending on the interests and experience of the applicant and could include, (i) mapping recombination events using long read sequencing, (ii) mapping recombination in plant populations where recombination or epigenetic pathways are altered, and/or (iii) bioinformatics analysis of recombination events in long read data. We are interested to identify candidates with either strong experimental and/or computational backgrounds, or those wishing to combine both approaches.

The Henderson group investigates plant genome function, including control of recombination, in both model and crop plant species. We share laboratory space with the groups of Sir David Baulcombe and Dr Jake Harris, who investigate intersecting questions in plant genomes and epigenetics. Our group is located in the Department of Plant Sciences, which is a diverse and inclusive workplace, where a wide range of plant sciences research and teaching is performed.

Informal enquiries are welcome and should be sent directly to Prof. Henderson on irb5@cam.ac.uk

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please notice that if you have not received any news from us 1 month after the closing date you should consider that on this occasion your application has not been successful.

Please quote reference PD33079 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information
  • PDRA Further Particulars
  • Department/Location

    Department of Plant Sciences

    Salary

    £34,308-£42,155

    Reference

    PD33079

    Category

    Research

    Published

    7 September 2022

    Closing date

    30 September 2022

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