Postdoctoral Research Associate-UICentre For Drug Discovery

University of Illinois at Chicago

United States

December 1, 2021

Description

Title:

Postdoctoral Research Associate-UICentre For Drug Discovery (Job ID #154915)

Department:

Pharmacy/UICentre For Drug Discovery

Category:

Postdoc Res Assoc

Location:

Chicago

Close Date:

12/01/2021

Description:

This position works with the UICentre leadership and project teams to develop, execute and effectively communicate results of molecular, biochemical and cellular assays in support of drug discovery and development. The candidate will support the bioassay and HTS, hit-lead and lead optimization objectives of UICentre using highly specialized knowledge of state-of-the-art equipment and methodologies.

Duties:

Work within interdisciplinary research teams to design, develop and perform biochemical and cell- based assays in support of hit-to-lead or lead-to- candidate objectives for small molecule drug discovery teams.

Design and perform automation protocols to support high throughput screening for small molecule drug discovery efforts

Help manage small molecule libraries to support HTS

Work with cross functional teams to build appropriate strategies for translational science efforts

Effectively communicate bioassay approaches and options for discovery efforts to cross functional teams

Analyze bioassay data and manage transfer and storage of the data in database

Attend UICentre meetings and assist UICentre Director with scientific project management as needed.

Contribute to team discussions and decisions regarding new concepts for hit- to-lead optimization, and other

Organize data for presentations and publications, configure slide sets and present research reports to the UICentre members or other research groups

Perform other related duties and participate in special projects as assigned

Qualifications:

  • Ph.D. Degree in Biology, Molecular Biology, Biochemistry, Chemistry or related science
  • Experience with translational science approaches, small molecule drug discovery or high throughput screening
  • Strong knowledge and hands-on experience with enzyme- and cell-based assays
  • Experience with common analytical formats for high throughput screening such as FP, TR-FRET, ELISA, reporter assays and AlphaLISA
  • Knowledge and understanding of statistical validation process for screening assay development
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