Postdoctoral Research Associate - Johnson Lab

University of Illinois at Chicago

United States

January 31, 2022

Description

Title:

Postdoctoral Research Associate - Johnson Lab (Job ID #156993)

Department:

Pharmacy Practice

Category:

Postdoc Res Assoc

Location:

Chicago

Close Date:

01/31/2022

Description:

The University of Illinois at Chicago College of Pharmacy is recruiting for a post-doctoral fellow in the Department of Pharmacy Practice with Dr. Jeremy Johnson's laboratory supported by an NCI MERIT award.

Our laboratory focuses on the translational development of promising investigational agents. Preclinical studies will focus on evaluating isoprenylated xanthones for the disruption of androgen receptor (AR) functionality for prostate cancer. More specifically, we are interested in promoting degradation of the androgen receptor by small molecules. Our lab environment focuses on a team based model with active collaboration between scientists/fellows in our research group supporting pre-clinical and clinical based projects. Research in our group is supported by NCI (R37, R01, PREVENT), NIH-NICHD, USDA and foundations.

The College of Pharmacy at UIC, with campuses in Chicago and Rockford, is the #1 college of pharmacy in the state of Illinois and the #7 college in the US by US News & World Report. More information about the College and Department of Pharmacy Practice can be found at https: // pharmacy.uic.edu and https: // dpp.pharmacy.uic.edu

Duties:

  • Support pre-clinical and clinical studies in oncology/hematology.
  • Support processing and analysis of patient derived samples to establish molecular phenotypes to support ongoing clinical trials.
  • Conduct animal experiments for this project that include pharmacokinetic evaluation, athymic nude xenografts, and TRAMP mice.
  • Clinical studies in the UI Cancer Center include evaluating patient derived samples (e.g. plasma, skin, core biopsy) for analysis by qPCR, ELISA, immunoblot.
  • Possesses and applies comprehensive knowledge of research principles, concepts, practices and methods.
  • Qualifications:

  • PhD with training consistent with analytical chemistry, molecular biology, biomedical sciences or a related discipline.
  • A minimum of 1-2 years research experience in pharmacokinetic assay development.
  • Molecular biology experience with cloning and modifying proteins of interest will be preferred.
  • Preference will be given to applicants who demonstrate experience with prostate cancer cell culture (i.e. LNCaP, 22Rv1, VCaP), immunoblot, immunoprecipitation, immunofluorescence microscopy.
  • Displayed proficiency in lab research techniques required.
  • The successful candidate will have experience in a laboratory dedicated to translational research in Multiple Myeloma and cellular therapy and is currently funded for projects in the area of multiple myeloma and autologous transplant.
  • Attention to detail is essential to support written documentation, present findings, and project report submissions.
  • Screening of applicants will begin immediately and continue until the position is filled. Applications may only be submitted via the university's online application system. Please click the " Apply for position " button below.

    Please include the following in your application:

    1) A short cover letter including a brief statement of research experience (i.e. 1 page),

    2) A current CV and

    3) Contact information for three references.

    For fullest consideration, submit complete application materials by January 31, 2022. Applications must include all the following: letter of intent and curriculum vitae. Names and contact information of three references must be entered directly into the online application.