Postdoctoral Research Associate in Solute Carrier structural biology/Drug Design

University of Oxford
August 06, 2024
Offerd Salary:£36,024 - £44,263
Working address:N/A
Contract Type:fixed-term post is f
Working Time:Full time
Working type:N/A
Ref info:N/A

Postdoctoral Research Associate in Solute Carrier structural biology/Drug Design

Department of Biochemistry, South Parks Road, Oxford OX1 3QU


Salary (£) : £36,024 - £44,263 per annum

Location: Department of Biochemistry, South Parks Road, Oxford

Contract type: Fixed Term

Hours: Full-time

About the role

We are seeking to appoint a Postdoctoral Research Associate to join Prof Simon Newstead's lab in collaboration with Prof Philip Biggin (Oxford Biochemistry) and Prof Chris Schofield (Oxford Chemistry) to develop a computational pipeline to help design antibiotics with improved uptake into humans. This builds on a substantial body of work already performed by this team using a combination of advanced structural biology, computational techniques, and chemical synthesis. The aim of this post is to establish the mechanistic rules for proton coupling in Peptide Transporters and explore the development of inhibitors and modulators.

This full-time fixed-term post is funded by the BBSRC for up to 3 years in the first instance.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

What We Offer

Your happiness and wellbeing at work matters to us, so we offer a range of family friendly and financial benefits including:

• An excellent contributory pension scheme

• 38 days annual leave

• A comprehensive range of childcare services

• Family leave schemes

• Cycle loan scheme

• Membership to a variety of social and sports clubs

• Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.

About you

The successful applicant will work closely with the computational scientist employed in Prof Biggin's lab to develop a computational pipeline for improving antibiotic transport. Chemical synthesis support will be provided by colleagues in Prof Schofield's laboratory. The PDRA will therefore be expected to work very closely with PDRAs in our collaborator laboratories.

You will possess a PhD/DPhil or be near completion of a PhD/DPhil in Biochemistry, Structural Biology, Chemistry or related subject.

You are expected to have previous experience with eukaryotic membrane protein, as well as in mammalian or insect recombinant expression systems. You should be able to demonstrate competence and success in your thesis research (and postdoctoral work if appropriate). Excellent communications skills, the ability to write for publication and present research proposal results and results is also essential. You will also have demonstrable skills in teamwork.

Application Process

You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online application.

Only applications received before 12 noon on Tuesday 6th August 2024 can be considered with interviews for shortlisted candidates to be held as soon as possible thereafter.

Committed to equality and valuing diversity

Contact Person : HR Officer Vacancy ID : 173981 Contact Phone : Closing Date & Time : 06-Aug-2024 12:00 Pay Scale : STANDARD GRADE 7 Contact Email : [email protected] Salary (£) : £36,024 - £44,263 per annum

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