Postdoctoral position in single cell analysis of cell differentiation in
vivo (1.0 FTE)
The Van den Heuvel lab invites applications for a postdoctoral research
position in Developmental Biology. The focus of the project will be to reveal
the regulatory logic of cellular decision making in the context of animal
development. Specifically, we seek to better understand how precursor cells
commit to a specialized cellular fate, and how this is coordinated with a
permanent arrest of cell division. To address these questions, we will perform
detailed quantitative analyses of native cells during their differentiation
trajectory in the round worm Caenorhabditis elegans ( C. elegans ), in
combination with sophisticated genetic manipulation. This project will
incorporate the latest technologies in transcriptome, epigenome, and proteome
analysis, and will be carried out in close collaboration with specialists in
computational modeling (Ten Tusscher lab, Utrecht University), single-cell
analysis (Korswagen and Van Oudenaarden labs, Hubrecht Institute), and
proteomics techniques (Vermeulen lab, Radboud University Nijmegen).
We are looking for a curious and ambitious junior scientist who:
holds a PhD degree in biology, biomedical sciences or a related field;
has a strong interest in molecular biology;
has previous experience with independent research, and preferably worked
with genetic model organisms, advanced microscopy, and/or bioinformatic
has been trained in scientific writing, communication and presentation in
has the motivation to work in an ambitious, multidisciplinary and
international research team.
a full-time position for two years;
embedding in a great team of top Life Sciences Researchers;
depending on previous qualifications and experience, a gross salary
ranging between €2,836 and €5,211 per month (scale 10/11 of the
Collective Labour Agreement of Dutch Universities) for a full-time
8% holiday bonus and 8.3% end-of-year bonus;
a pension scheme, partially paid parental leave, and flexible employment
conditions (based on the Collective Labour Agreement Dutch
About the organization
Research in the Developmental Biology Division makes use of a
multidisciplinary strategy in genetic animal model systems ( C. elegans ,
zebrafish, organoids) to acquire a deeper fundamental understanding of the
processes that determine development and health. Three teams that use the C.
elegans model work closely together and share experience in C. elegans
genetics and biology, as well as technologies (latest CRISPR knock-
in/knockout strategies, live imaging, super-resolution microscopy) on a daily
basis. In addition, there are frequent interactions and joint lab meetings
with the neighbouring labs (Cell Biology, Neurobiology, Biophysics), the
nearby Theoretical Biology and Bioinformatics groups. These groups and a newly
started Genome Biology & Epigenetics group form part of the Institute of
Biodynamics and Biocomplexity (IBB).
If you have any questions about this position, please contact Sander van den
Heuvel, via S.J.L.vandenHeuvel@uu.nl. Do you have a question about the
application procedure? Please send an email to firstname.lastname@example.org.
Everyone deserves to feel at home at our university. We welcome employees with
a wide variety of backgrounds and perspectives. If you have the expertise and
experience to excel in this role, please respond via the “Apply” button!
a one-page cover letter describing the reasons behind your interest in the
a curriculum vitae;
name, telephone number, and email address of three references.
The application deadline is