7 Nov 2023
Job InformationOrganisation/Company
University of Strasbourg
Department
Institut de Science et d'Ingénierie Supramoléculaires (ISIS)
Research Field
Chemistry » Organic chemistry
Researcher Profile
Recognised Researcher (R2)
Country
France
Application Deadline
1 Dec 2023 - 12:00 (Europe/Paris)
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
37.5
Is the job funded through the EU Research Framework Programme?
H2020 / ERC
Reference Number
101001752
Is the Job related to staff position within a Research Infrastructure?
No
Offer DescriptionWe are seeking to hire an outstanding postdoctoral scientist to join the Laboratory of Chemical Catalysis at the Institute of Science and Supramolecular Engineering (Institut de Science at d'Ingénierie Supramoleculaires), University of Strasbourg, France.
The successful candidate will work in prebiotic chemistry (chemical origin of life) as part of the ERC Consolidator project MetabolismOrigins. The expected start date is flexible but preferably before May 2024.
Background: To understand what life is and how it came to be, prebiotic chemistry needs to explain why life uses the molecules, reactions, catalysts, pathways and overall organization that it does. Our laboratory is investigating whether the chemistry that led to life could have begun as a primitive nonenzymatic version of the biochemistry we know today. Initially, the primitive reaction network would have been promoted by inorganic catalysts. Some of the organic products of the reaction network would provide positive feedback to the existing reaction network through catalysis, allowing it to become more robust, specific, and capable of new functions. This catalytic feedback process would naturally lead to a system displaying progressively higher structural and catalytic complexity, eventually producing higher order catalysts (catalysts that make catalysts), such as genes. Our laboratory is investigating this hypothesis at multiple levels by evaluating how inorganic catalysts, metabolites (especially coenzymes), and nonequilibrium microenvironments can promote nonenzymatic versions of metabolic pathways and processes.
Candidate profile:
What we offer:
Prospective candidates are invited to submit an application (CV + a maximum one-page personal statement outlining why you are a good fit for this position + contact information for 2 referees) to Prof. Joseph Moran ([email protected]) before December 1, 2023 (12:00 UTC+1). Only complete applications will be considered.
Relevant publications: J. Am. Chem. Soc. 2023 , 145 , 21630; J. Am. Chem. Soc. 2023 , 145 , 13357; Nat. Commun. 2023 , 14 , 570; Angew. Chem. Int. Ed. 2022 , e202212932; Angew. Chem. Int. Ed. 2022 , e202212237; Angew. Chem. Int. Ed. 2022 , e202117211; J. Am. Chem. Soc. 2021 , 143 ,19099; Chem. Rev. 2020 , 120 , 7708; Nat. Ecol. Evol. 2020 , 4 , 534; Nature 2019 , 569 , 104; Nat. Ecol. Evol. 2018 , 2 , 1019; Nat. Ecol. Evol. 2017 , 1, 1716.
RequirementsResearch Field
Chemistry » Organic chemistry
Education Level
PhD or equivalent
Languages
ENGLISH
Level
Excellent
Research Field
Chemistry » Organic chemistry
Additional Information
Work Location(s)
Number of offers available
1
Company/Institute
University of Strasbourg
Country
France
City
Strasbourg
Postal Code
67000
Geofield
Where to applyCity
Strasbourg
Website
https: // isis.unistra.fr
Street
8 allée Gaspard Monge
Postal Code
67000
STATUS: EXPIRED