Postdoctoral Position In Organic Chemistry – Flowcap Project

Universities and Institutes of France

France

September 30, 2022

Description

  • Organisation/Company: CEA Saclay
  • Research Field: Chemistry
  • Researcher Profile: First Stage Researcher (R1) Recognised Researcher (R2) Established Researcher (R3) Leading Researcher (R4)
  • Application Deadline: 30/09/2022 00:00 - Europe/Brussels
  • Location: France › Saclay
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Offer Starting Date: 01/02/2023
  • In the context of personalized medicine where treatment must be adapted to the patient, antibodies and more particularly ADCs (antibody-drug conjugates) are expanding rapidly, with 11 compounds on the market in 2021 and more than 300 in clinical trials. However, despite their undoubted interest, many challenges remain particularly for controlling the number of cytotoxic molecules bound to the antibody and for determining their precise binding sites.

    FlowCAP project is an innovative project aiming at improving current antibody- cytotoxic compound coupling methodologies in order to access different ADCs via innovative robust processes. The use of flow chemistry will ultimately allow the development of safe production of large quantities of ADCs. They could also serve as a starting point for the development of new ADCs, functionalized by drugs of various kinds or by therapeutic radioisotopes, and thus push the ADC concept even further.

    Offer Requirements Specific Requirements

    Candidates should have:

    - Strong skills in organic chemistry

    - A PhD in organic chemistry

    - Excellent knowledge, both written and oral, of English

    - A real skill to work in large collaboration and autonomously

    - Strong interpersonal, organizational and communication skills are a must.

    Contact Information
  • Organisation/Company: CEA Saclay
  • Organisation Type: Public Research Institution
  • Country: France
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