Postdoctoral Position In Organic Chemistry/Chemical Biology

Universities and Institutes of France

France

October 13, 2022

Description

  • Organisation/Company: CEA, SCBM
  • Research Field: Chemistry
  • Researcher Profile: Recognised Researcher (R2) Established Researcher (R3)
  • Application Deadline: 13/10/2022 00:00 - Europe/Brussels
  • Location: France › Saclay
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Offer Starting Date: 02/01/2023
  • In the frame of a collaborative CEA project aiming at developing new technologies based on chemical biology approaches for therapy and diagnosis (see for example J. Med Chem. 2022, 65, 6953–6968), we wish to recruit a highly motivated post-doctoral researcher for a 12 months contract. The project involves the development of novel technologies (site-specific radio labeling and digital imaging) for monitoring in vivo performances of protein–drug conjugates. In the framework of this project, we aim to devise tools for effective radioactive labelling of Abs and ADCs for PK/PD studies. Several format of biologics (IgG, Fragment of antibody (Fab) and nanobody/VHH) will be labelled and their in vivo distribution will be studied and compared with non-site-specific state of the art technologies.

    For recent publication from our laboratory, see: J. Med Chem. 2022, 65, 6953–6968 J. Am. Chem. Soc. 2021, 143, 5659–5665; ACS Catal. 2021, 11, 2968−2976; Chem. Commun., 2020, 56, 11677-11680; Angew. Chem. Int. Ed. 2020, 59, 13490 –13495; J. Am. Chem. Soc. 2019, 141, 780-784; Angew. Chem. Int. Ed. 2018, 57, 9744.

    Offer Requirements Specific Requirements

    The successful candidate is a skilled organic chemist, holder of a PhD in organic chemistry, with a strong scientific record, a high motivation. Good verbal and written communication skills and a flair for teamwork are required.

    Contact Information
  • Organisation/Company: CEA, SCBM
  • Organisation Type: Public Research Institution
  • Website: https: // tinyurl.com/CEAJOLIOT-SCBM-LMC-eng
  • Country: France
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