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Postdoctoral position in metabolomics
100%, Zurich, fixed-term
The Institute of Molecular Systems Biology at ETH Zurich is inviting
applications for a Postdoctoral position in the laboratory of Professor Dr
The group of Dr Zamboni researches the function and regulation of metabolism.
In particular, the group is attracted by (i) systems in which metabolism or
metabolites drive phenotypic differentiation, (ii) problems of biomedical
relevance, and (iii) cases that are especially complex or technically
challenging. To tackle such problems, the group adopts cutting-edge mass
spectrometry (i.e. metabolomics, lipidomics, and quantitative 13C metabolic
flux analysis) and computational methods.
A key focus of the group is on the development of high-throughput methods,
which allow to rapidly screen large cohorts of, i.e. clinical samples, drug
libraries, or mutant collections. By combining high-resolution, untargeted
mass spectrometry and newly engineered software pipelines, the group has
become very efficient in analyzing studies with tens of thousands of samples
without compromising quality and coverage. Beyond internal R&D projects, the
group of Dr Zamboni is heavily involved in external collaborations, both
national and international. The group is tightly embedded in the Swiss
initiatives on personalized health (e.g. www. sfa-phrt.ch). Here, the main
focus is on complementing metabolomics and lipidomics data with tools that
assist in data integration and interpretation.
Contribute to novel developments with original ideas and technical
expertise in mass spectrometry.
Conduct MS analyses on various systems (LC-MS, GC-MS, QQQ, TOFs, and
Supervise instrument maintenance.
Assist and train non-expert colleagues on planning, executing, and
Communicate with collaborators and vendors.
Participate in teaching activities.
Doctoral degree in analytical chemistry or a related field.
Strong background in mass spectrometry (e.g. metabolomics, lipidomics, or
Excellent technical skills in LC-HRMS (DDA and DIA workflows), with
practical experience in the routine maintenance of MS instruments and LC
Genuine passion for metabolomics
Proactive personality and excellent communication skills.
Further, any expertise in cheminformatics, computational mass spectrometry, or
programming is of advantage.
ETH Zurich is one of the world's leading universities specialising in science
and technology. We are renowned for our excellent education, cutting-edge
fundamental research and direct transfer of new knowledge into society. Over
30,000 people from more than 120 countries find our university to be a place
that promotes independent thinking and an environment that inspires
excellence. Located in the heart of Europe, yet forging connections all over
the world, we work together to develop solutions for the global challenges of
today and tomorrow.
Working, teaching and research at ETH Zurich Get connected
We look forward to receiving your online application with the following
A motivation letter stating own visions and specifying any past experience
that is aligned with the job profile
Name and contact of two referees
Please note that we exclusively accept applications submitted through our
online application portal. Applications via email or postal services will not
Further information about the Institute of Molecular Systems Biology can be
found on our website, www. imsb.ethz.ch. Questions regarding the position
should be directed to Dr Nicola Zamboni, email firstname.lastname@example.org (no
Apply online now