Do you want to contribute to top quality medical research?
The position is based at unit of Molecular Neurobiology (MBB), at Karolinska
Institutet, Stockholm, Sweden.
The Castelo-Branco research group is interested in the molecular mechanisms
defining the epigenetic state of cells of the oligodendrocyte lineage. We are
focused on how interplay between transcription factors, non-coding RNAs and
chromatin modifying enzymes contribute to the transition between states within
the oligodendrocyte lineage, with the aim to design epigenetic based-therapies
to induce regeneration (remyelination) in demyelinating diseases, such as
multiple sclerosis. Our research group has performed single cell omics and
identified several cell states within the oligodendrocyte lineage in
development and disease (Science 2016, Dev Cell 2018, Nature Medicine 2018,
Nature 2019, Nature Biotechnology 2021, among others). Our findings suggest
that oligodendrocyte lineage cells might present other functional properties
than previously thought.
We have ongoing several projects with single-cell omics and more recently in
spatial transcriptomics and epigenomics, and the successful candidate will be
actively working in specific projects. The successful candidate will be
integrated in a multidisciplinary team comprising computational, molecular and
A creative and inspiring environment full of expertise and curiosity. Our
research group is based at the Department of Medical Biochemistry and
Biophysics (MBB), at the Karolinska Institutet (KI), Stockholm, Sweden,
within the Unit of Molecular Neurobiology. The Unit of Molecular Neurobiology
has presently seven research groups, focused on several aspects of
development, stem cell biology, neuroscience and cancer, providing a unique
critical mass and expertize, and vibrant scientific environment. Karolinska
Institutet is one of the world's leading medical universities. Our vision is
to pursue the development of knowledge about life and to promote a better
health for all. At Karolinska Institutet, we conduct successful medical
research and hold the largest range of medical education in Sweden. Karolinska
Institutet collaborates with prominent universities from all around the world,
which ensures opportunities for international exchanges. Employees also have
access to our modern gym for free and receive reimbursements for medical care.
We are looking for highly motivated, driven, inquisitive, enthusiastic person
interested in our area of research, and ready to explore new avenues in
science. The candidate should have a collaborative approach to research,
working productively in a team and contributing to a good social environment
in the laboratory. The applicant must have a PhD degree, and either strong
experience in single cell omics, spatial omics and/or
Scholarships for postdoctoral qualification can be established for foreign
researchers who place their qualifications in Sweden. The purpose of
scholarships for postdoctoral qualification is to promote internationalization
and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a
maximum of two years within a four year period following the receipt of a
doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a
doctorate or a foreign degree deemed to be equivalent to a doctorate.
Applicants who have not completed a doctorate at the end of the application
period may also apply, provided that all requirements for a completed degree
are met before the (intended) start date of the post doctoral education.
The head of the department determines whether their previous training and
scholarly qualifications correspond to a Swedish doctorate or higher.
Location : Solna
Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on
a six months basis. In exceptional cases, shorter periods may be acceptable.
Submit your application and supporting documents through the Varbi recruitment
system. Use the button in the top right corner and follow the instructions.
An employment application must contain the following documents in English:
A complete curriculum vitae, including date of PhD defense, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work (nor more than 4 pages)
A selected list of publications (no more than 2 pages)
A personal letter highlighting previous scientific accomplishments, technical expertize and why the candidate is interested in joining the host lab (no more than one page)
Reference letters if available
Want to make a difference? Join us and contribute to better health for
|First day of employment
|Last application date
||16.Jan.2022 11:59 PM CET