Postdoctoral Position | Biophysical Chemistry



March 31, 2022


At the Max Planck Institute for Medical Research, one of the 86 institutes of the Max Planck Society for the Advancement of Science, physicists, chemists and biologists create knowledge of long-term relevance to life and basic medical sciences. Currently, our around 270 employees are divided into four departments and one Max Planck Research Group. In addition, the institute is part of the Heidelberg Mannheim Health & Life Science Alliance - an association of the leading life science research institutions in the region.

Our research

The Department of Optical Nanoscopy (Prof. Dr. Stefan W. Hell) at the Max Planck Institute for Medical Research, Heidelberg, invites applications for a postdoctoral position dedicated to the design and realization of experimental strategies for the direct observation of the structure and dynamics of macromolecular motors or other dynamic assemblies with the highest spatial and temporal resolution in live cells.

The recently introduced MINFLUX (Balzarotti et al., Science 2017) and MINSTED (Weber et al., Nature Photonics 2021) concepts have unlocked the door to minimally invasive, low-light-level analysis of the structure and the dynamics of biomolecular complexes(e.g. Gwosch et al., Nature Methods 2020) in living cells in 4D at the nanoscale. The unprecedented capabilities available in the department include experiments at 1-nm resolution.

The ambitious project aims at unraveling structure-function relationships and molecular mechanisms of macromolecular assemblies and motors. The works also entails the development of sample preparation methodologies and imaging strategies using the latest nanoscopy approaches such as MINFLUX. The sample design will be performed in close collaboration with the organic chemists and physicists from the Department of Optical Nanoscopy at the MPI for Medical Research.

Your profile

Candidates should have an excellent track record, high motivation, and broad scientific interests. They should hold a doctoral degree with focus in biophysical chemistry, chemical biology or biophysics and enjoy working in the lab. Relevant postdoctoral experience are an advantage. Practical experience with fluorescence nanoscopy, and a strong background in photophysics, photochemistry and/or molecular biology are desirable. Successful candidates will join a multidisciplinary and international team. The working language of the project will be English.

We offer

We offer excellent laboratory facilities tailored to the needs of the project. Payment is based on the TVöD guidelines. The position is limited to two years with a possibility of extension.

Your application

Please submit your application, including a cover letter (explaining background andmotivation), your CV and complete transcripts via e-mail as a single PDF file with the code number 01/2022 preferably until March 31, 2022 to (excellent applications will be considered earlier and/or year-round).

For further information , please contact Prof. Dr. Stefan W. Hell (

For general questions , please contact Mrs. Höfer-Elfner ( or Ms. Sabrina Giacalone ( from human resources.

The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. The Max Planck Society strives for gender and diversity equality. We welcome applications from all backgrounds. Furthermore, the Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply. A daycare center for children is located near the institute.