Postdoctoral Medicinal Chemist Fellow

Indiana University Purdue University Indianapolis

United States

December 20, 2021


Posting Details Title Postdoctoral Medicinal Chemist Fellow

Specific Title Appointment Type Postdoctoral Fellow Department IUSM - Medicine - Clinical Pharmacology Campus IU School of Medicine Indianapolis Position Summary

The Department of Medicine, Division of Clinical Pharmacology, at Indiana University School of Medicine ( IUSM), Indianapolis, Indiana is seeking a highly motivated, passionate, and proactive Chemist to perform early drug discovery research within a dynamic and innovative academic setting. The successful candidate will join a dynamic, interdisciplinary team of scientists focused on early-stage drug discovery research and will work in collaboration with scientists at Indiana University, Bloomington, and the Indiana Biosciences Research Institute. Given the academic, biotech-like nature of our goals, the cultural fit of a successful candidate is an important criterion for success. Desired characteristics include a “can do” attitude, a high level of curiosity, and the ability to work collaboratively with others.

The primary responsibilities of this postdoctoral fellow will be designing and synthesizing analogs and evaluating structure activity relationships (SAR) to optimize the potency, physicochemical and ADME properties, pharmacokinetics, safety, and in vivo efficacy of lead molecules. In collaboration with other scientists, you will be evaluating biological targets, developing strategies to synthesize small molecule ligands for these targets, reviewing physicochemical and biological data, and optimizing potential drug candidates for sufficient target engagement in vivo. Results will be published in high-impact, peer-reviewed journals.

About the School and Department: The Indiana University School of Medicine https: // is the largest medical school in the US and is annually ranked among the top medical schools in the US by US News & World Report. Please visit https:// for additional information about the Department of Medicine.

About the Campus: To learn more about the Indiana University-Purdue University Indianapolis campus, please visit: https:// www.

Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the largest concentrations of health sciences companies in the nation. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life – the city possesses a variety of professional sports, arts venues, and outdoor recreation areas. Residents of this dynamic city, and surrounding suburbs, enjoy leading educational systems and top-ranked universities, paired with a diverse population. Indianapolis International Airport is a top-ranked international airport, being named “Best Airport in North America” by Airports Council International for many years. For additional information on life in Indy: https: //

As the nation's largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity, and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.

Basic Qualifications

Doctorate or terminal degree required. Prefer an individual with a PhD degree in organic chemistry, medicinal chemistry, chemical biology, or a closely related field.

Preferred qualifications include: Knowledge of general chemistry, organic synthesis, and related laboratory techniques.

Expert in synthetic methodologies, retro-synthetic analysis, purification, and verification of chemical structure.

Experience with analytical techniques and methodologies (e.g. HPLC, LCMS, gas chromatography, NMR, mass spec, etc.).

Basic skills in communication, word processing, database searching, data entry, and data analysis (e.g. ChemDraw, Reaxys, SciFinder, Microsoft Office365, including Word, Excel, and PowerPoint.).

Department Contact for Questions

Stephanie Wallace

Additional Qualifications Special Instructions Priority Application Review Deadline Expected Start Date OAA # IUSM012302016

Supplemental Questions

Required fields are indicated with an asterisk ().

  • How did you hear about this position?
  • Personal Contact: At Professional Meeting or Conference
  • Personal Contact: Direct Contact by Search Committee
  • Personal Contact: Referred by colleague or advisor
  • Personal Contact: School of Medicine recruiter
  • Personal Contact: IUHP Physician Recruiter
  • Announcement: Other Journal or Magazine
  • Announcement: Other Website
  • Are you a dual career partner (your partner or spouse is already being recruited)?
  • Yes
  • No
  • Applicant Documents

    Required Documents

  • Curriculum Vitae
  • Letter of Application
  • Optional Documents

  • List Of References