Title Postdoctoral Medicinal Chemist Fellow
Appointment Type Postdoctoral Fellow
Department IUSM - Medicine - Clinical Pharmacology
Campus IU School of Medicine Indianapolis
The Department of Medicine, Division of Clinical Pharmacology, at Indiana
University School of Medicine ( IUSM), Indianapolis, Indiana is seeking a
highly motivated, passionate, and proactive Chemist to perform early drug
discovery research within a dynamic and innovative academic setting. The
successful candidate will join a dynamic, interdisciplinary team of scientists
focused on early-stage drug discovery research and will work in collaboration
with scientists at Indiana University, Bloomington, and the Indiana
Biosciences Research Institute. Given the academic, biotech-like nature of our
goals, the cultural fit of a successful candidate is an important criterion
for success. Desired characteristics include a “can do” attitude, a high level
of curiosity, and the ability to work collaboratively with others.
The primary responsibilities of this postdoctoral fellow will be designing and
synthesizing analogs and evaluating structure activity relationships (SAR)
to optimize the potency, physicochemical and ADME properties,
pharmacokinetics, safety, and in vivo efficacy of lead molecules. In
collaboration with other scientists, you will be evaluating biological
targets, developing strategies to synthesize small molecule ligands for these
targets, reviewing physicochemical and biological data, and optimizing
potential drug candidates for sufficient target engagement in vivo. Results
will be published in high-impact, peer-reviewed journals.
About the School and Department: The Indiana University School of Medicine
https: // medicine.iu.edu/ is the largest medical school in the US and is
annually ranked among the top medical schools in the US by US News & World
Report. Please visit https:// medicine.iupui.edu for additional information
about the Department of Medicine.
About the Campus: To learn more about the Indiana University-Purdue University
Indianapolis campus, please visit: https:// www. iupui.edu/about/
Indianapolis is the capital and most populous city in the State of Indiana. It
is growing economically thanks to a strong corporate base anchored by the life
sciences. Indiana is home to one of the largest concentrations of health
sciences companies in the nation. Indianapolis has a sophisticated blend of
charm and culture with a wonderful balance of business and leisure. The
growing residential base is supported by rich amenities and quality of life –
the city possesses a variety of professional sports, arts venues, and outdoor
recreation areas. Residents of this dynamic city, and surrounding suburbs,
enjoy leading educational systems and top-ranked universities, paired with a
diverse population. Indianapolis International Airport is a top-ranked
international airport, being named “Best Airport in North America” by Airports
Council International for many years. For additional information on life in
Indy: https: // faculty.medicine.iu.edu/relocation/.
As the nation's largest medical school, IUSM is committed to being an
institution that not only reflects the diversity of the learners we teach and
the patient populations we serve, but also pursues the values of diversity,
equity, and inclusion that inform academic excellence. We desire candidates
who enhance our representational diversity, as well as those whose work
contributes to equitable and inclusive learning and working environments for
our students, staff, and faculty. IUSM strives to take an anti-racist stance,
regularly evaluating and updating its policies, procedures, and practices to
confer equitable opportunities for contribution and advancement for all
members of our community. We invite individuals who will join us in our
mission to advance racial equity to transform health and wellbeing for all
throughout the state of Indiana.
Doctorate or terminal degree required. Prefer an individual with a PhD degree
in organic chemistry, medicinal chemistry, chemical biology, or a closely
Preferred qualifications include:
Knowledge of general chemistry, organic synthesis, and related laboratory
Expert in synthetic methodologies, retro-synthetic analysis, purification,
and verification of chemical structure.
Experience with analytical techniques and methodologies (e.g. HPLC, LCMS,
gas chromatography, NMR, mass spec, etc.).
Basic skills in communication, word processing, database searching, data
entry, and data analysis (e.g. ChemDraw, Reaxys, SciFinder, Microsoft
Office365, including Word, Excel, and PowerPoint.).
Department Contact for Questions
Priority Application Review Deadline
Expected Start Date
OAA # IUSM012302016
Required fields are indicated with an asterisk ().
How did you hear about this position?
Personal Contact: At Professional Meeting or Conference
Personal Contact: Direct Contact by Search Committee
Personal Contact: Referred by colleague or advisor
Personal Contact: School of Medicine recruiter
Personal Contact: IUHP Physician Recruiter
Announcement: Other Journal or Magazine
Announcement: Other Website
Are you a dual career partner (your partner or spouse is already being recruited)?
Letter of Application
List Of References