Title Postdoctoral Fellow in Host-Microbe Interaction
Appointment Status Non-Tenure Track
Department IU Bloomington Biology
A postdoctoral position is available as part of a collaborative project
between the Newton (https: // discogenome.wordpress.com/) and Hardy
(https:// thehardylab.mystrikingly.com/) laboratories, in the Department of
Biology, Indiana University, Bloomington.
This position is part of an NSF Rules of Life: Microbiome Theory and
Mechanisms award focused on identifying how microbes alter the
Successful host-associated microbes sculpt host cell biology in ways that are
useful to them. Often, these changes in host biology alter the ability of
other microbes to colonize, protecting the host niche for the first microbe.
For example, colonization of insects with Wolbachia endosymbionts can preclude
infection by viruses. This fact has led to the deployment of Wolbachia-
infected mosquitos across the globe to limit the transmission of vectored
diseases. We have identified RNA modifications induced by Wolbachia that
directly alter Drosophila cell biology and affect the ability of viruses to
colonize. Wolbachia upregulates a host methyltransferase to limit virus
replication and our preliminary data suggest that the virus genome itself is
modified in a Wolbachia infected cell, altering mRNA stability. These data
lead us to ask “How does a microbial symbiont alter the epitranscriptomic
landscape of host cells?”
The ideal candidate will have experience in Drosophila, molecular virology,
and/or bioinformatics. The candidate will be trained in molecular virology,
and the use of direct sequencing approaches (PacBio and ONT) to identify
The position will be funded for up to three years, with the potential to
extend for an additional year.
A Ph.D. in microbiology, virology, bioinformatics, entomology, or a related
field is required at time of appointment.
Department Contact for Questions
Inquiries about the position can be directed to Irene Newton
All other inquiries can be directed to Jeremy Bennett
Salary and Rank Salary will be commensurate with experience, and full
benefits are included.
To apply, please submit (i) a letter of application, (ii) a full CV,
(iii) a statement of research interests, and (iv) contact information for
three references electronically to
The College of Arts and Sciences is committed to building and supporting a
diverse, inclusive, and equitable community of students and scholars.
For Best Consideration Date
Expected Start Date 03/01/2022
OAA # 22105-03
Required fields are indicated with an asterisk ().
Letter of Application
List Of References