Postdoctoral Associate (P.I.: Dr. Bradley Aouizerat)

New York University

United States

February 6, 2022

Description

Postdoctoral Associate (P.I.: Dr. Bradley Aouizerat) New York University: NYU - NY: College of Dentistry: Oral and

Maxillofacial Surgery: Bluestone Center for Clinical Research

Location

New York, NY

Open Date

Jul 10, 2020

Description

Postdoctoral Associate (Molecular Epidemiology lab)

The NYU Bluestone Center for Clinical Research Molecular Epidemiology Laboratory is recruiting one highly motivated bioinformatic Postdoctoral Associate (2-year appointment), who aspires to become an independent academic researcher in the areas of molecular epidemiology and computational biology.

The Molecular Epidemiology Laboratory, led by Dr. Bradley Aouizerat, is a group of experimental and computational scientists dedicated to understanding the risk factors for and the mechanisms that underlie chronic disease (primarily HIV and cancer), their treatment (i.e., HIV antiretroviral therapy), and its sequelae (i.e., pain, fatigue, neuropathy). Research approaches employed by the group includes a combination of dry (e.g., bioinformatics) and wet (e.g., molecular biology) approaches. The Laboratory works closely with other laboratories with expertise in animal and cell models to permit accelerated translation of processes of interest identified in human data. Commonly applied approaches relevant to the current position include:

  • Leveraging publicly available molecular data (i.e., GWAS, transcriptomic, epigenomic, proteomic)
  • Generating molecular data from cohort studies
  • Applying and developing novel multi-omic analysis
  • Identifying therapeutic targets.
  • Optimization of DNA and RNA capture techniques
  • Single-cell genomics applications
  • POSITION OVERVIEW

    The Postdoctoral Associate will work primarily with Professor Bradley Aouizerat, MS, PhD, on NIH-funded studies aimed at identifying genetic (i.e., DNA variation, gene expression) and epigenetic (e.g. DNA methylation) alterations associated with risk factors for and consequences of HIV-infection or with cancer. The role will involve analyzing high throughput genomic data including DNA methylation array and sequencing data, as well as RNAseq (bulk and single cell) data, performing integrative analyses and contributing to dissemination of results. The applicant will be expected to have capacity to work independently as well as collaboratively with other members in the lab, to have experience in developing workflows for sequencing data and ability to multitask.

    The Postdoctoral Associate will analyze and manipulate data generated from both internal and external sources, use, modify, or create pipelines and reporting software. By applying a variety of software and technologies, the Postdoctoral Associate will perform rapid, incremental analysis required to best process and interpret the large amount of data generated in a molecular epidemiology laboratory.

    The Postdoctoral Associate will communicate bioinformatics analysis to lab members and collaborators, ensure the validity and reliability of data and methods at all times, and maintain accurate and complete records of all analysis projects. The Postdoctoral Associate will identify and help to develop suitable techniques for the analysis and visualization of data, and build and maintain the associated computational resources (i.e. software packages, databases, or web-based analysis and visualization tools), and will maintain all code and programs used for analysis and tool development with suitable source control.

    Other research expectations include authoring and co-authoring several manuscripts per year, assisting grant writing with and also being responsible for grant submissions to support their research, collaborating with other investigators, and attending professional conferences.

    JOB SPECIFIC TASKS

  • Assist Dr. Aouizerat with design and conduct of research projects.
  • Apply, modify, or develop analytical pipelines for manipulating genomic datasets and interpret results appropriately to ensure accuracy and reliability of those pipelines. Examples of data routinely analyzed include array-based (i.e., SNP, gene expression, DNA methylation), RNA sequencing (bulk and single cell), DNA sequencing, and methylation capture sequencing.
  • Acquire, update and analyze data from internal (e.g., Aouizerat or affiliated laboratories, Core Facilities) or external (e.g., TCGA, UCSC Genome Browser, 1000Genomes, dbGaP) sources, document system changes, write and maintain documentation for end users.
  • Collaborate with others in the research team, including statisticians, clinicians, molecular biologists, molecular epidemiologists, and computational biologists to design studies and implement computational applications.
  • Prepare and contribute to dissemination of research findings (i.e., manuscripts, lab meeting presentations, presentations at scientific meetings).
  • Qualifications

    EDUCATION AND REQUIRED SKILLS EXPERIENCE

    Required:

  • Bachelors degree in biology, chemistry or other life sciences
  • Ph.D. in Bioinformatics, Statistics, Mathematics, Physics, Computer Sciences or related discipline
  • Excellent programming skills with multiple programming languages and computational environments, including UNIX-style operating systems (e.g., Linux), command line interfaces, R, perl/python, BASH, Matlab, or similar, and SQL or other database software
  • Knowledge of current bioinformatics approaches, databases, and best practices
  • Able to work both independently and collaboratively
  • Be highly motivated, have excellent analytical, problem-solving, and time management skills
  • Excellent oral and written English communication skills
  • Outstanding interpersonal and teamwork skills
  • Excellent analytical, problem-solving, organizational and time management skills.
  • Preferred:

  • Experience in use of machine learning approaches
  • Experience with and knowledge of biological sciences, especially genetics and molecular biology
  • Experience with nextgen sequencing data analysis; experience using standard nextgen sequencing analysis software (including samtools, GATK, Picard, bedtools)
  • Experience working with TCGA, COSMIC, 1000 Genomes, ENCODE, or GTEx data
  • Programming skills in C++ or Java a plus
  • 1-2 prior post-doctoral experience
  • PHYSICAL REQUIREMENTS AND ENVIRONMENTAL CONDITIONS

    The physical requirements and environmental conditions of this position consist primarily of:

  • Continuous mental and visual attention, requiring sustained attention and observation
  • Ability to work at a PC monitor for most of the work day
  • Application Instructions

    Applicants should submit: 1) Cover letter; 2) Curriculum Vitae; and 3) Names and contact information of at least two professional references. To access the application, please click the "Apply Now" button located on the right.

    Application Process

    This institution is using Interfolio's Faculty Search to conduct this search. Applicants to this position receive a free Dossier account and can send all application materials, including confidential letters of recommendation, free of charge.

    Apply Now

    Powered by

    Opens in new window

    Equal Employment Opportunity Statement

    For people in the EU, click here for information on your privacy rights under GDPR:www. nyu.edu/it/gdpr

    NYU is an Equal Opportunity Employer and is committed to a policy of equal treatment and opportunity in every aspect of its recruitment and hiring process without regard to age, alienage, caregiver status, childbirth, citizenship status, color, creed, disability, domestic violence victim status, ethnicity, familial status, gender and/or gender identity or expression, marital status, military status, national origin, parental status, partnership status, predisposing genetic characteristics, pregnancy, race, religion, reproductive health decision making, sex, sexual orientation, unemployment status, veteran status, or any other legally protected basis. Women, racial and ethnic minorities, persons of minority sexual orientation or gender identity, individuals with disabilities, and veterans are encouraged to apply for vacant positions at all levels.

    Sustainability Statement

    NYU aims to be among the greenest urban campuses in the country and carbon neutral by 2040. Learn more at nyu.edu/sustainability

    Similar Jobs

    New York University

    United States Jan 7, 2022

    Add to favorites Read more...

    Assistant Research Scientist (P.I.: Dr. Bradley Aouizerat)

    Assistant Research Scientist (P.I.: Dr. Bradley Aouizerat) New York Assistant Research Scientist (Molecular Epidemiology lab) The NYU Bluestone Center for Clinical Research Molecular Epidemiology Laboratory is searching for an outstanding Assistant Research Scientist (Computational Biologist),...

    Salk Institute for Biological Studies

    United States Dec 24, 2021

    Add to favorites Read more...

    Research Assistant II (Mass Spectrometry) - Molecular and Cell Biology Laboratory, Dr. Christian Metallo

    history, or length of your employment history if less, including all positions maintenance and operation of gas chromatography-mass spectrometry (GC-MS) systems for metabolomics analysis of cell, organoid, and tissue samples. flux analysis to these systems...

    Germany Universities

    Germany Dec 24, 2021

    Add to favorites Read more...

    Open Position: Ph.D. (f/m) in Computational Biology/BioinformaticsLudwig-Maximilians-Universität • SyNergy: Cluster for Systems Neurology • München

    Subjects Computational Biology Description The Helmholtz Center in Munich (HMGU), Germany, is a member of one of the leading research associations in Europe - the Helmholtz Association of German Research Centers. We are looking for...

    About the employer

    Since its founding in 1831, NYU has been an innovator in higher education, reaching out to an emerging middle class, embracing an urban identity and professional focus, and promoting a global vision that informs its 19 schools and colleges. Today,...