Postdoctor - Nuclear Envelope Budding In Neurodegenerative Diseases And Cancer

Göteborg University
February 07, 2023
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Offerd Salary:Negotiation
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Contract Type:Fixed-term for two a
Working Time:Full time
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The University of Gothenburg tackles society's challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Department of Chemistry and Molecular Biology conducts high-quality research and education in chemical sciences and molecular life sciences. Our research and education focuses on a deep understanding of chemical and biological processes in cells and in the environment.

We address important societal issues such as antibiotic resistance, cancer, brain diseases, environmental problems and climate change. In this way, we contribute to achieving the UN's global goals for sustainable development in the areas of good health and well-being, sustainable energy for all, sustainable cities and communities, and combating climate change.

The department is an international environment with interdisciplinary collaborations in both research and education, and contributes strongly to the University of Gothenburg's top ranking in life science.

The department is responsible for postgraduate education in the subject area Natural Sciences with a focus on chemistry, biophysics, biology and educational science. In addition, the department hosts educational programs in molecular biology, genomics and systems biology, chemistry, organic chemistry and pharmaceutical chemistry, as well as prescription education. The department collaborates with various societal actors such as schools, business and authorities. The Department of Chemistry and Molecular Biology has around 200 employees. We are located in central premises both on Campus Johanneberg and on Campus Medicinareberget in Gothenburg.

Johanna Höög's research group focuses on electron microscopy and tomography after cryopreparation of cells. Our research is interdisciplinary between the medical, cellular and structural biology fields.

Duties

The successful applicant will grow and maintain yeast and fly stocks. The scientist will design and execute experiments investigating nuclear envelope budding in both yeast models of neurodegenerative diseases, and in fly brains using both light and electron microscopy. The successful applicant will screen for nuclear envelope budding events in multiple fly tissues. Special focus will be fly brain dissection with further processing for electron microscopy. The postdoc will also examine if nuclear envelope budding is increased in cancer.

The work will be done in collaboration with a PhD student and all work in the group is performed in English.

Qualifications

The applicant must have completed a doctoral degree in the field of biological sciences. The ideal candidate should also have a strong background in yeast genetics and expertise in molecular and cell biology. The applicant must have conducted productive research in relevant disciplines, and experience with modern electron microscopy (such as cryo-preparation of cells) is a must. Good work ability and social ability are important. Excellent English language skills, both orally and in writing, are a requirement.

Experience of the fruit fly (Drosophila melanogaster) and the yeast (Saccharomyces cerevisiae) as a model system is very meritorious. Expert knowledge in drosophila molecular genetics and familiarity with multiple tissues and pathways is preferred. In addition, previous experience with yeast and Drosophila models of proteotoxicity and human disease-linked neurotoxic proteins will be beneficial.

Employment

Fixed-term for two and a half years full-time (100%) at the Department of Chemistry and Molecular Biology.

Contact information for the post

If you have any questions about the position, please contact Johanna Höög, [email protected]

Unions

Union representatives at the University of Gothenburg can be found here: https: // www. gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Application

To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg's recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.

Your application must include:

  • A cover letter with the applicant's justification for the application, i.e., that describes how the applicant meets the selection criteria.
  • A list of qualifications (CV).
  • Applications must be received by: 2023-02-07

    The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

    Salaries are set individually at the University.

    In accordance with the National Archives of Sweden's regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

    In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

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