Postdoctor In Microbiota And Metabolism

Göteborg University
December 06, 2023
Offerd Salary:Negotiation
Working address:N/A
Contract Type:Fixed-term employmen
Working Time:Negotigation
Working type:N/A
Ref info:N/A

The University of Gothenburg tackles society's challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Department of Molecular and Clinical Medicine, at the Institute of Medicine, conducts translational research primarily on metabolism, diabetes, obesity and cardiovascular disease in order to improve health and healthcare in the community. The overall goal is to create an excellent translational research environment of a very high international standard.

Approximately 50% of the cells in the human body are of microbial origin. By combining clinical materials and gnotobiotic animal models, we have shown that the gut microbiota affects our physiology and metabolism. Our working hypothesis is that several of the microbiota's effects on our physiology are mediated via metabolites that the bacteria produce. We are now recruiting a postdoctoral fellow to investigate how one of these metabolites, imidazole propionate, affects the intestinal function and development of cardiometabolic disease and cancer.

Subject area

Microbiota and metabolism

Subject area description

The gut microbiota contains 1000-fold more genes than our own genome contain. Several of these genes encode enzymes that can produce bioactive metabolites. Even if we just started to scratch the surface it has started to become obvious that several of these metabolites may have profound effect on our physiology and metabolism. For example, they can increase or decrease insulin sensitivity and other metabolic phenotypes. Here we will investigate how imidazole propionate affects the intestinal function and cellular composition with respect of cancer and cardiometabolic disease.


Establish animal models to study cancer and metabolic disease. Thereafter, treat mice with imidazole propionate and evaluate how the molecule affects cell composition and cell division in the gut. In addition, the applicant will establish 2- and 3-dimensional organoid systems from the gut. Histologic analyses of mice in relation to cellular composition and proliferation. Analyses of gene expression and hormone release.


To qualify as a postdoctoral researcher the applicant should hold a PhD in a relevant subject. Since postdoctoral constitutes a qualifying appointment for junior researchers, we aim to target those who have a doctoral degree not older than 3 years.

Assessment criteria

Strong background in performing animal studies and experience with gut organoids are requirements. Previous experience working with microscope and microbial metabolites are strong merits. Analysis of 2- and 3-dimensional organoids from both small and large intestine for cellular composition and proliferation are merits. International experience in the relevant research area is meritorious. It is essential that the applicant can interact with other researchers and clinicians within a greater team and great emphasis will be placed on personal suitability such as being able to take own initiatives and being flexible. It is a requirement to be able to communicate well in English, both verbally and in writing.


Type of employment: Fixed-term employment, 36 months Extent: 100 % Location: Institute of Medicine, Gothenburg First day of employment: As soon as possible or according to agreement

Contact information

Fredrik Bäckhed Professor +46(0)31-3427833 [email protected]

Malin Levin Head of Department [email protected]


Union representatives at the University of Gothenburg can be found here: https: // www.


Please attach PhD certificate with the application, if the PhD certificate has not yet been issued, it needs to be attached latest at the time when the employment decision is to be made.

Submit your application via the University of Gothenburg's recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.

Applications must be received by: 2023-12-06.

Information for International Applicants

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:

https: // www. https: // www.

Visit the webpage Join us - jobs and career for more information on the Institute of Medicine and what opportunities we have for you. Discover our world-class research and research infrastructure, as well as what the benefits are for you and your family.

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden's regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

From this employer

Recent blogs

Recent news