Lund University, Faculty of Medicine, Dept of Laboratory Medicine, Lund
Lund University was founded in 1666 and is repeatedly ranked among the world's
top 100 universities. The University has around 44 000 students and more than
8 000 staff based in Lund, Helsingborg and Malmö. We are united in our efforts
to understand, explain and improve our world and the human condition.
The Faculty of Medicine is a part of Lund University, and is responsible for
education and research within medicine and healthcare. Our academic programs
are closely linked with the healthcare system and are firmly anchored in the
faculty's strong research tradition. Our research spans a broad field within
experimental preclinical research, near-patient clinical research and health
sciences research. The Faculty of Medicine, with its 1,800 employees and 2,700
students in Lund and Malmö, is a knowledge-intensive meeting place for
students, teachers and researchers from all over the world.
The Department of Laboratory Medicine is one of six departments at Lund
University's Faculty of Medicine. We conduct leading research, both broad and
specialised, within the field of laboratory medicine, focusing on the onset of
disease and how we can improve diagnostics and treatment for patients. Some of
our strongest areas with world-class research deal with cancer, genetics and
The Research Group
The Division of Translational Cancer Research (TCR) was founded 2013 in
conjunction with the formation of Lund University Cancer Center (LUCC) at
Medicon Village. TCR consists of ten research groups with different areas of
expertise, but together working on projects with the common goal of improving
cancer diagnostics and cancer therapy. Our multidisciplinary experimental
settings include human genetics, mouse genetics, human tissue platform, stem
cell biology and advanced imaging, aiming at creating novel diagnostic tools
and therapeutic modalities. The overarching goal at TCR is to open up new
horizons that will give the opportunities for novel diagnostic and treatment
modalities for cancer treatment. The kidney cancer group at TCR has for a long
time been focusing on studies of renal malignancies, with particular focus on
kidney cancer genetics in relation to the normal function of the many
different cell types in the kidney. Key biological processes in the
transformation process are studied using a variety of model systems and
techniques with the aim to identify targetable biomarkers for the disease.
Please read more about our research here.
Within the group, we aim to maintain a good working environment based on
mutual respect and consideration. We constantly strive to improve the
conditions for work, development and participation for all employees.
The employment is a full time position, time limited to two years, regulated
by central agreements regarding post-doctoral employments, with the desired
access date on November 15, 2021, or according to agreement.
Work assignments and area of expertise
In this postdoctoral project the main aim is to explore the links between loss
of the tumor suppressor gene VHL and transformation of normal proximal tubule
cells of the kidney. The task includes experimental studies on the
transcriptional cues activated by hypoxia. Different experimental models of
normal and malignant kidney cells will be subjected to treatment with a
variety of modulators of the hypoxic response and the treated cells will be
analysed with functional and genomic approaches. The obtained results will be
explored by using different bioinformatic tools.
The work will be highly team-oriented, both through internal and external
collaborations, which necessitates excellent collaboration and communication
skills to successfully fill this position. External collaborations may for
example involve local researchers from Lund University.
The main work duties are:
Studies of the hypoxic response in normal and malignant kidney cells
Application of both DNA- and RNA-based methods (WES, RNA-seq, single cell
seq etc.) for characterization of the model system
Providing expertise in bioinformatic analyses, in particular RNA-seq
Various types of analyses of patient cohorts with respect to disease
progression etc in relation to given biomarkers
Computational analyses of TMA based immunohistochemistry from large
patient cohorts and of proteomics data
Assessment criteria and other qualifications
This is a career development position primarily focused on research. The
position is intended as an initial step in a career, and the assessment of the
applicants will primarily be based on their research qualifications and
potential as researchers.
Particular emphasis will be placed on research skills within the subject.
For appointments to a post-doctoral position, the ability to develop and
conduct high quality research and also teaching skills will be evaluated as
part of the assessment criteria.
Appointment to a post-doctoral position requires that the applicant has a PhD,
or an international degree equivalent to a PhD, within a subject related to
the position, completed no more than three years before the last date for
applications. Under special circumstances, the doctoral degree can have been
Doctoral degree in a relevant research field (e.g. kidney biology or
Very good knowledge about, and documented practical experience of work
with model systems of normal and malignant kidney cells
Excellent knowledge in analyses of drug treatment response in vitro
Knowledge in transcriptomic analyses and visualisation
A good ability to master complex model systems in relation to normal
function of the kidney
At least 4 years of practical experience of working with cell biology in
general and kidney biology in particular
Very good oral and written communication skills in English
Great emphasis will be placed on personal suitability. You must have excellent
communication and collaboration skills as well as be able to conduct your work
independently and with high quality. Finally, you must demonstrate good
planning, structural and prioritization skills.
The following are merits for the position:
Experience of laboratory work, based on model systems of normal and
Experience from high through-put drug screening
Previous project management experience
Terms of employment
This is a full-time, fixed-term employment of a maximum of 2 years. The period
of employment is determined in accordance with the agreement “Avtal om
tidsbegränsad anställning som postdoktor” (“Agreement on fixed-term
employment as a post-doctoral fellow”) between Lund University, SACO-S, OFR/S
and SEKO, dated 4 September 2008.
Instructions for your application
The application must contain a personal letter describing how you fulfill the
desired qualifications, a CV and diploma.
The university applies individual salary setting. Please indicate your salary
claim in your application.
Lund University welcomes applicants with diverse backgrounds and experiences.
We regard gender equality and diversity as a strength and an asset. We kindly
decline all sales and marketing contacts.
To apply, please click the button "Login and apply"
Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment November 15, 2021, or according to agreement
Salary Monthly salary
Number of positions 1
Working hours 100
County Skåne län
Reference number PA2021/2865
Håkan Axelson, recruiting manager, +46462226434
Emelie Falck, HR coordinator, 046-2220000
Last application date 26.Sep.2021 11:59 PM CEST
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