Postdoctor In Biomaterials

The University of Gothenburg tackles society's challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Institute of Clinical Sciences is one of six Institutes within Sahlgrenska Academy at the University of Gothenburg. We conduct research and education that puts people's health and quality of life in focus. We represent 16 different research areas and are divided into four sections. Through a fruitful collaboration with the healthcare and Sahlgrenska University Hospital, we have developed joint projects and meeting places that benefits both health care and research.

The Department of Biomaterials has an internationally leading position in the field of integration of implants and prostheses in hard and soft tissues. Our central focus is on novel, sustainable clinical implant solutions and fundamental mechanisms that determine successful implant-tissue interfaces (osseointegration) and functional performance. Our research is performed in interdisciplinary collaboration with national and international universities and companies, including clinicians and material scientists. Examples are studies on cell-material and cell-cell interactions (governmental strategic fund together with Chalmers; Area of Advance Materials) and osseointegrated amputation prostheses (Sahlgrenska University Hospital).

We now seek a postdoctoral researcher for continued studies on biodegradable magnesium implants with a focus on the morphological and cellular/biological processes during implant degradation and tissue healing in vivo. In a previous collaboration with international universities (EU project), the research group developed experimental models and analytical tools for studies of biodegradable implants. These studies have demonstrated relationships between the properties of magnesium implants and inflammation/mechanoinduction. Further, findings have revealed the importance of the composition of magnesium implants for osteogenesis and adipogenesis.

Biomaterials

Biomaterials is a multidisciplinary research subject with a focus on the interaction between materials and biology. The subject combines knowledge of a material's inherent properties with the adjacent tissue's cellular and molecular processes, morphological and biomechanical aspects under normal, compromised, and pathological conditions.

Healing around permanent metal implants is fairly well-characterized; however, our understanding of newer biodegradable metal implants is limited. The current position continues studies on degradable magnesium implants with an emphasis on the morphological and cellular/biological studies focused on the spatio-temporal processes of inflammation, mechanosensation and tissue regeneration at the interfaces between biodegradable magnesium implants, gas bubbles and tissues in vivo. The importance of compromised tissue conditions for these biological processes will also be explored experimentally and clinically.

The postdoctoral researcher will perform experimental in vivo studies, with a focus on the interfaces between biodegradable magnesium implants, gas bubbles and soft and hard tissues. The studies have a focus on acquiring spatio- temporal resolution of cells and extracellular matrices in these interfaces under normal and compromised conditions. The overall goal is to decipher the biological mechanisms which stimulate tissue regeneration in these models, the relationship with specific material properties, and potential negative tissue responses. The assignments include the planning and execution of experimental studies with subsequent biological analyses, data analysis and interpretation, exchange with materials science and clinical experts, writing of scientific reports and communication with other parts of society.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.

Requirements for the position are documented knowledge in biodegradable magnesium implants, light and electron microscopy, immunohistochemistry, and cell and molecular biology. Theoretical and methodological skills and experience in implants and their characterization, histomorphometry and experimental in vivo experimentation are required. Experience working or studying in international environments is an advantage. The applicant must have demonstrated competency in scientific writing in English and should have good general communication skills in English (both orally and in writing).

When evaluating the applicants, particular emphasis will be put on research skills in the relevant research field. The applicant should be able to work both independently and as part of a team. Accuracy and the abilities to cooperate and to take their own initiative are important qualities.

The employment is limited (temporary) for 24 months, 100 % of full-time and is placed at the Institute of Clinical Sciences, department of Biomaterials. Starting date; 2024-01-01

If you have any questions about the position, please contact Professor Anders Palmquist phone; +46 (0)768979058 or e-mail; [email protected]

Union representatives at the University of Gothenburg can be found here: https: // www. gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Application

Submit your application via the University of Gothenburg's recruitment portal by clicking the “Apply” button. The applicant is asked to provide a cover letter with a description of their research experience and future research aspirations (max 2 A4 pages) in addition to a CV and a list of publications. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.

Applications must be received by: 2023-11-20

Information for International Applicants

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The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden's regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.