Postdoc to Center for Translational Neuromedicine

Copenhagen University

Denmark

January 19, 2022

Description

We are looking for a highly motivated and dynamic researcher at the level of postdoc for a 2-year position to commence in May 2022 or after agreement.

The position focus on the glymphatic system efflux pathways in neurodegenerative diseases.

Information on the department can be found at: www. ctn.ku.dk.

Our research group Center for Translational Neuromedicine currently has 50 employees and students and is divided into 3 labs. CTN is characterized by a highly ambitious research environment. The postdoc will be part of the Nedergaard lab.

Being part of the Nedergaard lab offers an opportunity to work in a multi- disciplinary lab engaged in neuroscience with a focus on the basic biology of glial cells in the CNS and the role of astrocytes in several neurological diseases, including stroke, spinal cord injury, epilepsy, tremor, and ALS. Research is aimed at defining new strategies for the treatment of neurological diseases that target astrocytic dysfunction. CTN is part of the Faculty of Health and Medical Sciences, University of Copenhagen, and is located at Panum. The Center comprises modern laboratories and excellent facilities within neuroscience. The project that we are recruiting for focuses on glymphatic system efflux pathways in neurodegenerative diseases in rodent models using multiple optical imaging approaches.

Your job The discovery of a novel macroscopic clearance system – the brain glymphatics – posits the existence of a functional drainage system that can transport proteins and extracellular fluid from the brain in a manner similar to peripheral organs. We strive for the determination of neurodegenerative diseases impact the clearance of metabolites along the glymphatics efflux pathways, as well as its connections to the peripheral lymphatics.

Your tasks would include the design and implementation of experimental workflows, which allow the visualization and manipulation of fluid fluxes along the glymphatic efflux pathways. Also, you are expected to train and mentor students at Master level.

We expect that you be an expert within the following tasks:

  • Immunohistochemistry
  • Viral delivery of therapeutics
  • Optical in vivo imaging
  • Profile We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

    Essential experience and skills:

  • You have a PhD in neuroscience, neurobiology or equivalent
  • You are highly experienced in glial biology and neurodegenerative diseases, light microscopy, rodent microsurgery, tissue clearing, histology and image processing
  • You are trained in the analysis of brain fluid dynamics
  • Proficient communication skills and ability to work in teams
  • Excellent English skills written and spoken
  • Desirable experience and skills:

  • Knowledge on glial biology and neuroanatomy
  • Experience on glymphatic system studies
  • Experience on rodent microsurgery, histology and tissue clearing
  • Knowledge on light microscopy and image analysis
  • Experience on mentoring of students
  • Place of employment

    The place of employment is at Center for Translational Neuromedicine, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and state-of-the-art equipment.

    Terms of employment The employment as postdoc is a full time and fixed-term position for 2 years. Starting date is 1 May 2022.

    Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at 33,600 DKK/ approx. 4,416 Euro (2021-level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

    Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

    The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.

    You will report to Dr. Maiken Nedergaard.

    Questions For further information please contact Professor Maiken Nedergaard, nedergaard@sund.ku.dk or Center Administrator Ann Christensen, ann.christensen@sund.ku.dk.

    International applicants may find this link useful: www. ism.ku.dk (International Staff Mobility).

    Application procedure Only online applications are accepted. The following must be included: • Cover letter stating the interest in and qualifications for the project as well as list of techniques • Full CV • Diploma and transcripts of records, both from Master's and PhD degrees • Publication list • Possible references

    The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

    Application deadline: 19 January 2022

    Apply via link or:Jobportal

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