Eawag, the Swiss Federal Institute of Aquatic Science and Technology, is an internationally networked aquatic research institute within the ETH Domain (Swiss Federal Institutes of Technology). Eawag conducts research, education and expert consulting to achieve the dual goals of meeting direct human needs for water and maintaining the function and integrity of aquatic ecosystems.
The Department of Environmental Toxicology (Utox) has an opening for a
PostDoc position to computationally model the Fish Invitrome toward a virtual fish
Are you an expert in computational modelling and excited to apply your skills to solution-driven research in order to develop alternatives to conventional animal toxicity testing with fish? Then this position might be the right one for you and we would love to welcome you to our dynamic and innovation-driven team of environmental toxicologists.
Building on our successes to establish fish cell line-based in vitro assay procedures to predict chemical impact on fish, we aim to advance our “Fish Invitrome” framework by (i) expanding its experimental capabilities toward a broader panel of cell lines and impacts of chemical toxicity and (ii) integrating this experimental work via mechanistic computational models. This position is for an individual who would like to develop the computational part to allow for quantitative in vitro-to-in-vivo extrapolation (IVIVE). Different types of models can be envisioned alone or in combination, such as quantitative Adverse Outcome Pathways (AOP) and ToxicoKinetic-ToxicoDynamic (TKTD) models.
As part of the modelling efforts, you will have an opportunity to closely interact with two PhD students on the project and other colleagues who perform experimental work. Moreover, we collaborate with social sciences colleagues from Eawag and Utrecht University to accelerate the acceptance and implementation of our framework by taking regulatory routines and procedures, as well as industrial innovation practices, into account. Hence, this position also offers opportunity for strong stakeholder interactions to move the research to where it counts.
As the Postdoctoral candidate for this project you should have a PhD in natural sciences or engineering with computational modelling expertise. Knowhow in IVIVE-related modelling and an interest in stakeholder interactions would be an asset. Solid work ethics, mature teamwork attitude and good English skills are essential.
Eawag is a modern employer and offers an excellent working environment where staff can contribute their strengths, experience and ways of thinking. We promote gender equality and are committed to staff diversity and inclusion. The compatibility of career and family is of central importance to us. For more information about Eawag and our work conditions, please consult www. eawag.ch and www. eawag.ch/en/aboutus/working/employment.
Deadline for applications is 31 May 2023. Your application should include a cover letter explaining your research background and motivation to apply for this position, a CV with list of publications, copies of your academic qualifications and contact information for two references. The project runs until the end of 2026; the starting date for this position is as soon as possible upon agreement.
For further information, please contact Prof. Dr Kristin Schirmer.
We look forward to receiving your application. Please send it through this webpage, as any other way of applying will not be considered. A click on the button below will take you directly to the application form.
Applications from employment agencies/personnel consultants are not welcome and will not be considered.
Eawag: Swiss Federal Institute of Aquatic Science and Technology